The Preventive and Therapeutic Effects of Probiotics in Allergic Diseases Via Immune Modulation
2016
Kim, Y.H., Korea University, Seoul, Republic of Korea | Choi, C.Y., Korea University, Seoul, Republic of Korea | Chun, T., Korea University, Seoul, Republic of Korea
The demand to develop more safe and efficient methods for treating allergic patient is now continuously growing due to the increasing prevalence of allergic diseases. Probiotics are endogenous microbial flora that gives health benefits within hosts. Probiotics are now considered as one of solutions to treat allergic patients since recent evidence shows that some of probiotics have immunomodulatory function. Also, the treatment of probiotics to patients is relatively safer than other anti-inflammatory agents. In this review, we summarized on immunomodulatory function of some probiotics which show preventive or therapeutic effects on major allergic diseases such as atopic dermatitis, allergic rhinitis, asthma, or food allergy. Based on previous literature, the treatment of probiotics can alleviate the symptoms of allergic diseases via balancing Th1/Th2 response or increasing the number of regulatory T (Treg) cells.
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