Human Health Risk Assessment from Lead Exposure through Consumption of Raw Cow Milk from Free-Range Cattle Reared in the Vicinity of a Lead–Zinc Mine in Kabwe
Golden Zyambo; John Yabe; Kaampwe Muzandu; Ethel M’kandawire; Kennedy Choongo; Andrew Kataba; Kenneth Chawinga; Allan Liazambi; Shouta M. M Nakayama; Hokuto Nakata; Mayumi Ishizuka
Lead (Pb) contamination in the environment affects both humans and animals. Chronic exposure to Pb via dietary intake of animal products such as milk from contaminated areas poses a health risk to consumers: therefore, the present study investigated Pb contamination in cow milk and its health risk impact on humans through consumption of milk from cattle reared in the proximity of a Pb&ndash:Zn mine in Kabwe, Zambia. Fresh milk samples were collected from cows from Kang&rsquo:omba (KN), Kafulamse (KF), Mpima (MP), Mukobeko (MK), and Munga (MN) farming areas. Pb determination was performed using Graphite Flame Absorption Atomic Spectrophotometry (GFAAS). Cow milk Pb levels showed different concentration patterns according to season, distance, and location of the farms from the Pb&ndash:Zn mine. The overall mean Pb levels were ranged 0.60&ndash:2.22 µ:g/kg and 0.50&ndash:4.24 µ:g/kg in the wet and dry seasons, respectively. The mean Pb concentration, chronic daily intake (CDIs), target hazard quotients (THQs), and incremental lifetime cancer risk (ILCR) results obtained were all within the permissible limits of 20 µ:g/kg, 3 and 12.5 µ:g/kg-BW/day, <:1 and 10&minus:4 to10&minus:6, respectively. In conclusion, although Pb was detected in milk from cows reared in Kabwe, the health risk effects of Pb exposure associated with the consumption of milk in both adults and children were negligible.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
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