A connectome and analysis of the adult Drosophila central brain
2020
Louis K Scheffer | C Shan Xu | Michal Januszewski | Zhiyuan Lu | Shin-ya Takemura | Kenneth J Hayworth | Gary B Huang | Kazunori Shinomiya | Jeremy Maitlin-Shepard | Stuart Berg | Jody Clements | Philip M Hubbard | William T Katz | Lowell Umayam | Ting Zhao | David Ackerman | Tim Blakely | John Bogovic | Tom Dolafi | Dagmar Kainmueller | Takashi Kawase | Khaled A Khairy | Laramie Leavitt | Peter H Li | Larry Lindsey | Nicole Neubarth | Donald J Olbris | Hideo Otsuna | Eric T Trautman | Masayoshi Ito | Alexander S Bates | Jens Goldammer | Tanya Wolff | Robert Svirskas | Philipp Schlegel | Erika Neace | Christopher J Knecht | Chelsea X Alvarado | Dennis A Bailey | Samantha Ballinger | Jolanta A Borycz | Brandon S Canino | Natasha Cheatham | Michael Cook | Marisa Dreher | Octave Duclos | Bryon Eubanks | Kelli Fairbanks | Samantha Finley | Nora Forknall | Audrey Francis | Gary Patrick Hopkins | Emily M Joyce | SungJin Kim | Nicole A Kirk | Julie Kovalyak | Shirley A Lauchie | Alanna Lohff | Charli Maldonado | Emily A Manley | Sari McLin | Caroline Mooney | Miatta Ndama | Omotara Ogundeyi | Nneoma Okeoma | Christopher Ordish | Nicholas Padilla | Christopher M Patrick | Tyler Paterson | Elliott E Phillips | Emily M Phillips | Neha Rampally | Caitlin Ribeiro | Madelaine K Robertson | Jon Thomson Rymer | Sean M Ryan | Megan Sammons | Anne K Scott | Ashley L Scott | Aya Shinomiya | Claire Smith | Kelsey Smith | Natalie L Smith | Margaret A Sobeski | Alia Suleiman | Jackie Swift | Satoko Takemura | Iris Talebi | Dorota Tarnogorska | Emily Tenshaw | Temour Tokhi | John J Walsh | Tansy Yang | Jane Anne Horne | Feng Li | Ruchi Parekh | Patricia K Rivlin | Vivek Jayaraman | Marta Costa | Gregory SXE Jefferis | Kei Ito | Stephan Saalfeld | Reed George | Ian A Meinertzhagen | Gerald M Rubin | Harald F Hess | Viren Jain | Stephen M Plaza
The neural circuits responsible for animal behavior remain largely unknown. We summarize new methods and present the circuitry of a large fraction of the brain of the fruit fly Drosophila melanogaster. Improved methods include new procedures to prepare, image, align, segment, find synapses in, and proofread such large data sets. We define cell types, refine computational compartments, and provide an exhaustive atlas of cell examples and types, many of them novel. We provide detailed circuits consisting of neurons and their chemical synapses for most of the central brain. We make the data public and simplify access, reducing the effort needed to answer circuit questions, and provide procedures linking the neurons defined by our analysis with genetic reagents. Biologically, we examine distributions of connection strengths, neural motifs on different scales, electrical consequences of compartmentalization, and evidence that maximizing packing density is an important criterion in the evolution of the fly’s brain.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
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