Effect of immunotherapy with a saline phenol extract of allogeneic tumour on E-rosette counts in horn cancer-affected cattle [India]

Batra, U.K.; Sadana, J.R.; Gupta, R.K.P. . College of Veterinary Sciences

Effect of immunotherapy with a saline phenol extract of allogeneic tumour on E-rosette counts in horn cancer-affected cattle [India]

1986

Batra, U.K. | Sadana, J.R. | Gupta, R.K.P. (Haryana Agricultural Univ., Hissar (India). College of Veterinary Sciences)

The mean percentage of cells forming rosettes with 2-aminoethyl isothiouronium bromide-treated sheep erythrocytes, E(AET).RFC, in the peripheral blood of 10 cattle with horn cancer was significantly lower than in unaffected controls. Immunotherapy with a saline phenol extract of allogeneic tumour tissue resulted in a gradual increase in the mean percentage of E(AET).RFC on each subsequent week. The increase was statistically significant from the second week onwards and, on the sixth week, the percentage of E(AET).RFC in cattle with cancer closely approximated the value in unaffected controls.

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