Feline immunodeficiency virus: prevalence, disease associations and isolation [Victoria; cats]

Friend, S.C.E.; Lording, P.M.; Birch, C.J. . Virology Dept.; Studdert, M.J. . School of Veterinary Science

Feline immunodeficiency virus: prevalence, disease associations and isolation [Victoria; cats]

1990

Friend, S.C.E. | Lording, P.M. (Central Veterinary Diagnostic Lab., Surrey Hills (Australia)) | Birch, C.J. (Fairfield Hospital, Fairfield (Australia). Virology Dept.) | Studdert, M.J. (Melbourne Univ., Parkville (Australia). School of Veterinary Science)

Of 467 cat serums tested for antibody to feline immunodeficiency virus (FIV) 120 (26 percent) were positive. The average age of positive cats was 7.5 years (range 1 to 16 years), and 67 percent were male. Of 110 serums collected in 1980, 27 (24.5 percent) were positive. A wide variety of clinical signs including oral cavity disease, anorexia, weight loss, lethargy, depression, fever, respiratory and urinary tract disease, conjunctivitis, abscesses, anaemia and lymphadenopathy were observed in the cats with serum antibody. There was often a history of chronic disease or recurrence of particular or various clinical signs in these cats. FIV was isolated from 4 of 8 FIV antibody positive cats by cocultivation of patient lymphocytes with donor lymphocytes in the presence of interleukin 2.

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