Immunosuppression in dogs with pyoderma and/or demodicosis
1997
Toman, M. | Krejci, J. | Faldyna, M. | Barta, O. (Vyzkumny Ustav Veterinarniho Lekarstvi, Brno (Czech Republic)) | Svoboda, M. | Rybnicek, J.
The occurrence of decreased activity of the immune system was studied in a group of 66 dogs with various combinations of pyoderma and demodicosis. Immunosuppression was found in 19 (28.8%) cases. Immunosuppression was rare in dogs with demodicosis and did not appear without a concurrent pyoderma. An increase in the neutrophil counts and total serum immunoglobulin levels significant was found in dogs with demodicosis combined with pyoderma. On the contrary, marked immunosuppression was detected in dogs with deep pyoderma. A considerable immunosuppression was present in 7 of 10 German shepherds dog pyoderma (GSP). Significant depressions were found in phagocyte and lymphocyte activity. Immunosuppression was observed in 4 of 9 dogs in other breeds with uncomplicated deep pyoderma. All groups of dogs with pyoderma showed a significant increase in total serum immunoglobulins. Conclusion form these findings is that deep pyoderma more than demodicosis was concerned with immunosuppression. German shepherds with deep pyoderma expressed immunosuppresion more than other breeds.
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