Bioactivity and action mechanism of green propolis against Pythium aphanidermatum.
2019
PAZIN, W. M. | SANTOS, S. N. | QUEIROZ, S. C. do N. de | BAGATOLLI, L. A. | SOARES, A. E. E. | MELO, I. S. de | ITO, A. S. | WALLANCE MOREIRA PAZIN, FFCLRP-USP; SUIKINAI NOBRE SANTOS; SONIA CLAUDIA DO N DE QUEIROZ, CNPMA; LUIS ALBERTO BAGATOLLI, Instituto de Investigaciones Medicas Mercedes y Martín Ferreyra/; ADEMILSON ESPENCER EGEA SOARES, FMRP-USP; ITAMAR SOARES DE MELO, CNPMA; AMANDO SIUITI ITO, FFCLRP-USP.
Abstract: We have established how natural compounds from green propolis collected by the species Apis mellifera act against the growth of Pythium aphanidermatum. On the basis of mass spectrometry (Q-ToF MS), we determined that Artepillin C, the major constituent of green propolis, underlies the effect and displays activity against P. aphanidermatum at a minimal inhibitory concentration of 750 ?g.ml-1. Biophysical studies based on model membranes showed that this inhibitory effect may be linked with a membrane-related phenomenon: Artepillin C increases the permeability of membranes with relatively high fluidity in their lateral structure, a feature that is in line with the lipid composition reported for the cytoplasmic membrane of P. aphanidermatum. Therefore, the present study supports the use of the effective and inexpensive green propolis to control the impact of the dangerous phytopathogen P. aphanidermatumon agriculture.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Empresa Brasileira de Pesquisa Agropecuária