Case report: Control of intestinal nematodes in captive Chlorocebus sabaeus

Cruz, Katalina; Corey, Tatiana M.; Vandenplas, Michel; Trelis, María; Osuna, Antonio; Kelly, Patrick J.

Case report: Control of intestinal nematodes in captive Chlorocebus sabaeus

2021

Cruz, Katalina(Ross University School of Veterinary Medicine Faculty of Veterinary Medicine ,University of Granada Institute of Biotechnology, Biochemistry and Molecular Parasitology Faculty of Sciences) | Corey, Tatiana M.(St Kitts Biomedical Research Foundation and Virscio) | Vandenplas, Michel(Ross University School of Veterinary Medicine Faculty of Veterinary Medicine) | Trelis, María(University of Valencia Faculty of Pharmacy Department of Parasitology,Health Research Institute La Fe Research Unit on Endocrinology, Nutrition and Clinical Dietetics) | Osuna, Antonio(University of Granada Institute of Biotechnology, Biochemistry and Molecular Parasitology Faculty of Sciences) | Kelly, Patrick J.(Ross University School of Veterinary Medicine Faculty of Veterinary Medicine)

There are limited data on the efficacy of antiparasitic treatments and husbandry methods to control nematode infections in captive populations of African green monkeys (AGMs), Chlorocebus sabaeus. In faecal egg count (FEC) tests, 10 of the 11 (91%) adult male AGMs captured from the large feral population on the island of St Kitts had evidence of nematode infections, mostly Capillaria (8/11, 73%), Trichuris trichiura (7/11, 64%) and strongylid species (7/11, 64%) specifically (hookworm and Trichostrongylus, 50/50), but also Strongyloides fuelleborni (1/11, 9%). When kept in individual cages with cleaning and feeding regimens to prevent reinfections and treated concurrently with ivermectin (300 µg/kg, given subcutaneously) and albendazole (10 mg/kg, given orally) daily for 3 days, 60% (6/10) of the AGMs were negative at a follow-up FEC at 3 months and by FEC and necropsy at the end of the study 5-8 months later. One monkey appeared to have been reinfected with T. trichiura after being negative by FEC at 3 months post-treatment. Four AGMs were positive for T. trichiura at the 3 month FEC follow-up but were negative at the end of the study after one further treatment regimen. Although initially being cleared of Capillaria following treatment, three AGMs were found to be infected at the end of the study. The ivermectin and albendazole treatment regimen coupled with good husbandry practices to prevent reinfections effectively controlled nematode infections in captive AGMs.

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