Differential allelic expression and co-expression revealed oxidative stress-dependent proteolysis as a key regulator of nelore beef tenderness.
2022
BRUSCADIN, J. J. | CARDOSO, T. F. | DINIZ, W. J. da S. | SOUZA, M. M. de | AFONSO, J. | VIEIRA, D. da S. | MALHEIROS, J. | ANDRADE, B. G. | PETRINI, J. | FERRAZ, J. B. S. | ZERLOTINI NETO, A. | MOURÃO, G. | COUTINHO, L. L. L | REGITANO, L. C. de A. | JENNIFER JESSICA BRUSCADIN, UNIVERSIDADE FEDERAL DE SÃO CARLOS; TAINÃ FIGUEIREDO CARDOSO; WELLISON JARLES DA SILVA DINIZ, AUBURN UNIVERSITY; MARCELA MARIA DE SOUZA, IOWA STATE UNIVERSITY; JULIANA AFONSO; DIELSON DA SILVA VIEIRA; JESSICA MALHEIROS, UNIVERSIDADE FEDERAL DA INTEGRAÇÃO LATINO-AMERICANA; BRUNO GABRIEL ANDRADE, MUNSTER TECHNOLOGICAL UNIVERSITY; JULIANA PETRINI, UNIVERSIDADE DE SÃO PAULO; JOSÉ BENTO STERMAN FERRAZ, UNIVERSIDADE DE SÃO PAULO; ADHEMAR ZERLOTINI NETO, CNPTIA; GERSON MOURÃO, UNIVERSIDADE DE SÃO PAULO; UIZ LEHMANN COUTINHO, UNIVERSIDADE DE SÃO PAULO; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
These findings suggest the impact of cis-regulatory variants on both the gene expression and phenotypic variation of Nelore muscle. These results can guide the investigation of regulatory variants affecting the expression of candidate genes for animal breeding, focusing on the genomic regions that affect the phenotypes of interest.
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