The Efficacy of Different Treatment Protocols in Pyometra with Respect to Reproductive Hormones and Indices in Dairy Cows

Early detection of the reproductive problems is fundamental to improve reproductive efficiency of dairy farms. Therefore, the study was performed to compare between two treatment protocols of pyometra to optimize reproductive performance of dairy cows. Based on rectal and ultrasonographic examinations, 30 cows suffered from pyometra were divided into; group1 (n=10) control group, group2 (n=10): treated with two injections of prostaglandin (PGF2α) plus systemic ceftiofur and group3 (n=10): treated with systemic ceftiofur. Ultrasonographic examination was performed before and 11 days after treatment. Blood samples were collected for analysis of progesterone (P4) and estradiol 17-ß just before and 11 days after treatment. Reproductive data was obtained regarding the1st and 2nd service conception rate (the 1st SCR and the 2nd SCR), number of services/conception (s/c) and days open. Ultrasonographic examination of the uterine horns appeared to be filled with hyperechoic granules in the lumen. However, the uterine horns at 11 days after treatment decreased in size and hyperechoic granules disappeared. No significant differences in P4 and estradiol 17- ß before and 11days after treatment. In cows received PGF2α+ ceftiofur, estradiol 17- ß was lower before treatment than 11 days after treatment. Significant improvement in the reproductive performance was recorded in treated cows with PGF2α+ceftiofur that manifested by marked increase in SCR and S/C as well as decrease in days open as compared with treated cows with ceftiofur only. It was concluded that double PGF2α injection+systemic ceftiofur is the best protocol to control pyometra that was pronounced by enhancement of reproductive performance in dairy cows.