Effect of dietary energy restriction on bone mineral content of mature rats
1986
Lee, C.J. | Panemangalore, M. | Wilson, K.
Males adult 16 months old Fischer-344 rats (7 per group) were fed a control diet ad libitum and energy modified diets restricted to 80% (R-80) and to 60%(R-60) of the control intake, while mineral and protein intakes were held constant at adequate levels. The control diet contained Ca, P, Mg & protein at 0.7, 0.4, 0.05 & 18.8%, respectively, and the two restricted diets contained higher levels of these nutrients to provide quantities equal to control diet when restricted to the respective energy level. After 16 weeks of feeding, significantly lower content in ash of the right femur (p less than 0.03) accompanied by lower content in Ca, P and Mg were observed in R-60 rats as compared to the control rats (p less than 0.02). Similarobservations were made on tibia and fibula. Thus, the present study suggests that adequate energy intake is essential for the maintenance of normal bone mineral content, and consequently the requirement of Ca, P and Mg could increase when dietary energy consumption is restricted.
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