Effect of 2,3,4-trihydroxyacetophenone (2,3,4-THAP) and 2,4,5-trihydroxybutyrophenone (2,4,5-THBP) on the rate of DL-DOPA oxidation by mushroom tyrosinase
1996
Kahn, V. | Zakin, V.
Various concentrations of 2,3,4-trihydroxyacetophenone (2,3,4-THAP) and 2,4,5-trihydroxybutyrophenone (2,4,5-THBP) have a synergistic effect on the rate of DL-3,4-dihydroxyphenylalanine (DL-DOPA) oxidation by mushroom tyrosinase as measured by absorbance at 475 nm. The synergism results from the ability of dopaquinone to nonenzymatically oxidize 2,3,4-THAP and 2,4,5-THBP to the corresponding alpha-quinone. Moreover, various concentrations of 2,3,4-THAP and 2,4,5-THBP prevent the enzymatic conversion of DL-DOPA to DOPA-melanin, probably due to the ability of these trihydroxyphenols to interact nonenzymatically with dopaquinone.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل National Agricultural Library