Overview and Research Progresses in Chemical Speciation and In Vitro Bioaccessibility Analyses of Airborne Particulate Trace Metals

Zhao, Zhen; Jing, Yuanshu; Luo, Xiao-San; Li, Hanhan; Tang, Mingwei

Overview and Research Progresses in Chemical Speciation and In Vitro Bioaccessibility Analyses of Airborne Particulate Trace Metals

2021

Zhao, Zhen | Jing, Yuanshu | Luo, Xiao-San | Li, Hanhan | Tang, Mingwei

PURPOSE OF REVIEW: As a priority environmental pollutant, toxic trace metals enriched in atmospheric particulate matters (PMs) pose potential threats to both ecological system and human health. To sufficiently clarify the relationships between airborne trace metals and environmental impacts, considering the chemical speciation and bioaccessibility of trace metals in PMs becomes necessary. RECENT FINDINGS: In this mini-review, such recent research progresses were summarized, including the concepts and developed methods for metal fractionation and bioaccessibility evaluation, especially the human body (lung)–related bioaccessible fractions of inhalable particle metals. Chemical extraction methods for different fractions and a compilation of in vitro bioaccessibility approaches for trace metals in PMs were presented. For future risk assessments and toxicity tests of atmospheric particulate metals, incorporating the bioaccessibility supported by standardized speciation methods are directions.

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