Effect of selenium on increasing free radical scavenging activities of polysaccharide extracts from a Se-enriched mushroom species of the genus Ganoderma
2008
Zhao, Lei | Zhao, Guanghua | Du, Ming | Zhao, Zhengdong | Xiao, Lixia | Hu, Xiaosong
Chemiluminescent analysis indicates that the polysaccharide extracts from Se-enriched G. lucidum (Se-GLPs) could protect DNA from hydroxyl radical oxidative damage in dose dependent manner. Moreover, Se-GLPs exhibited higher activities of scavenging superoxide and hydroxyl radicals than its analog from common G. lucidum extract as suggested by EPR measurement, indicating that Se plays an important role in increasing the antioxidant activities of the polysaccharide extracts. This was confirmed by spin-trapping experiments showing that at the same polysaccharide concentration, the activities of all the Se-GLPs samples in scavenging hydroxyl radical increased with the increase of Se content. Additionally, all Se-GLPs samples showed stronger activities of attenuating the production of superoxide radical than that of hydroxyl radical.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
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