Bone mineralization in former very low birth weight infants fed either human milk or commercial formula: one-year follow-up observation
1989
Abrams, S.A. | Schanler, R.J. | Tsang, R.C. | Garza, C.
We reported previously that bone mineral content in former very low birth weight infants fed human milk is lower at 16 and 25 weeks after hospitalization than in similar infants fed commercial formula. All infants had received fortified human milk during their hospitalization. At 16 and 25 postnatal weeks, human milk-fed infants also had lower ratios of bone mineral content to bone width, higher serum alkaline phosphatase activities, and lower serum phosphorus concentrations than infants fed commercial formula. The progression of bone mineralization in this high-risk population after the institution of a mixed diet is unknown. Our objective in this study was to determine whether maturation and the introduction of a mixed diet would affect the rate of bone mineralization in infants previously fed human milk.
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