Metal & Surfactant-Free oxidation of Quinoxalin-2(1H)-ones: Access to Quinoxaline-2,3-diones
2022
Li, Xuan | Zang, Jiawang | Wang, Shoucai | Kang, Chen | Xu, Jiawei | Jiang, Guangbin | Ji, Fanghua
An efficient and direct oxidative reaction for the construction of 1,4-dihydroquinoxaline-2,3-diones has been developed. A range of oxidative products are obtained with satisfactory yields (up to 99%). This practical method features transition metal free, surfactant free, chromatography free, mild reaction conditions, good functional group tolerance and easy scale-up synthesis. Furthermore, it provided a convenient approach for the synthesis of one kind of known inhibitor for α-glucosidase. This mechanistic study shows that this transformation is not a radical process.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
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