Coprisamides A and B, New Branched Cyclic Peptides from a Gut Bacterium of the Dung Beetle Copris tripartitus
2015
Um, Soohyun | Pak, So-hyŏn | Kim, JiHye | Park, Hyen Joo | Ko, Keebeom | Bang, Hea-Son | Lee, Sang Kook | Shin, Jongheon | Oh, Dong-Chan
Coprisamides A and B (1 and 2) were isolated from a bacterium in the gut of the dung beetle Copris tripartitus. Spectroscopic analysis revealed that the planar structures of 1 and 2 are novel cyclic heptapeptides bearing unusual units, such as β-methylaspartic acid and 2,3-diaminopropanoic acid branched to valine and 2-heptatrienyl cinnamic acid. Absolute configurations were established by chemical derivatization and chiroptical spectroscopy. The coprisamides displayed significant activity for induction of quinone reductase.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل National Agricultural Library