Characteristics of pigeon paramyxovirus serotype-1 isolates (PPMV-1) from the Russian Federation from 2001 to 2009
2013
Pchelkina, I. P. | Manin, T. B. | Kolosov, S. N. | Starov, S. K. | Andriyasov, A. V. | Chvala, I. A. | Drygin, V. V. | Yu, Q. | Miller, P. J. | Suarez, D. L.
Monitoring programs for highly dangerous avian diseases in the Russian Federation, from 2001 to 2009, detected 77 samples PCR-positive for avian paramyxovirus serotype-1 (APMV-1) isolates from sick or dead feral and domestic pigeons. Nucleotide sequences of the fusion (F) gene, including a nucleotide sequence encoding the F protein cleavage site, were determined for these isolates. All of the studied isolates possessed virulent F0 protein cleavage sites (112KRKKRF117, 112RRQKRF117 or 112KRQKRF117). Intracerebral pathogenicity index (ICPI) values determined for seven of the isolates exceeded the value of 0.7 (the range from 0.8 to 1.41). Based on the partial genome sequencing and phylogenetic analysis the isolates were assigned to two individual sub-lineages within class II genotype VIb. It was determined that most of these NDV isolates (70/77) recovered from the pigeons belonged to a relatively poorly studied sublineage VIb/2. The complete nucleotide sequence of the genome for the Pigeon/Russia/Vladimir/687/05 isolate of sub-lineage VIb/2 was determined.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
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