Synthesis of 2-alkyl-3-(indol- 2(or 3)-yl)-1,3-dihydroisoindol- 1-ones by amidoalkylation
2009
Andryukhova, N. P | Pozharskaya, O. A | Golubeva, G. A | Sviridova, L. A | Sadovoy, A.V
2-Alkyl-3-(indol-3-yl)-1,3-dihydroisoindol-1-ones have been obtained in good yield on amidoalkylation of indoles with 2-alkyl-3-hydroxyphthalides in chloroform at room temperature in the presence of catalytic quantities of boron trifluoride etherate. When a substituent is present at position 3 of the indole, attack is directed to position 2 of the indole nucleus.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
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