24-hour patterns of blood sugar, plasma insulin and free fatty acids in patients with primary endogenous hyperlipoproteinemia on isocaloric diets containing 30, 43 and 79 cal % carbohydrates
1979
Schellenberg, B. | Oster, P. | Vogel, G. | Heuck, C.C. | Schlierf, G.
Ten patients with primary, endogenous hypertriglyceridemia were fed three different isocaloric diets for 10 days each, containing either 30, 43 or 79% of calories as carbohydrate and 20% of calories from protein. On the last day of each dietary period, analyses of insulin, blood sugar and free fatty acids were conducted at frequent intervals. No differences were found in either fasting or diurnal blood sugars with the different diets. Insulin levels were positively correlated with the amount of carbohydrate in the diet. The carbohydrate content and circulating free fatty acids during waking hours were inversely correlated. Diurnal plasma lipid levels were lowest with the low fat regime and glucose tolerance was maintained. A high carbohydrate (but low sugar) diet is recommended for patients with endogenous hypertriglyceridemia.
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