Visible Light Assisted Photocatalytic [3 + 2] Azide–Alkyne “Click” Reaction for the Synthesis of 1,4-Substituted 1,2,3-Triazoles Using a Novel Bimetallic Ru–Mn Complex

Kumar, Pawan; Joshi, Chetan; Srivastava, Ambrish K.; Gupta, Piyush; Boukherroub, Rabah; Jain, Suman L.

Visible Light Assisted Photocatalytic [3 + 2] Azide–Alkyne “Click” Reaction for the Synthesis of 1,4-Substituted 1,2,3-Triazoles Using a Novel Bimetallic Ru–Mn Complex

2016

A photoactive bimetallic complex comprising a photosensitizer ruthenium unit and a catalytic Mn(I) unit connected via a bipyrimidine (bpm) bridging ligand is prepared and used for the first time for developing a light induced copper catalyzed [3 + 2] azide–alkyne “click” (CuAAC) reaction for the formation of 1,2,3-triazoles under visible light irradiation. The developed bimetallic complex exhibited enhanced activity as both the photosensitizer ruthenium unit as well as manganese catalyst unit are attached in a single molecule, providing efficient electron transfer for the photochemical reduction of Cu(II) to Cu(I) in situ which subsequently was used for the cycloaddition of azides with terminal alkynes to give 1,4-disubstituted 1,2,3-triazoles in the presence of triethylamine as a sacrificial donor.

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