Genome sequence, comparative analysis and population genetics of the domestic horse
2009
Wade, C.M. | Giulotto, E. | Sigurdsson, S. | Zoli, M. | Gnerre, S. | Imsland, F. | Lear, T.L. | Adelson, D.L. | Bailey, E. | Bellone, R.R. | Blöcker, H. | Distl, O. | Edgar, R.C. | Garber, M. | Leeb, T. | Mauceli, E. | Macleod, J.N. | Penedo, M.C.T. | Raison, J.M. | Sharpe, T. | Vogel, J. | Andersson, L. | Antczak, D.F. | Biagi, T. | Binns, M.M. | Chowdary, B.P. | Coleman, S.J. | Della Valle, G. | Fryc, S. | Guérin, Gerard | Hasegawa, T. | Hill, E.W. | Jurka, J. | Kiialainen, A. | Lindgren, G. | Liu, J. | Magnani, E. | Mickelson, J.R. | Murray, J. | Nergadze, S.G. | Onofrio, R. | Pedroni, S. | Piras, M.F. | Raudsepp, T. | Rocchi, M. | Roed, K.H. | Ryder, O.A. | Searle, S. | Skow, L. | Swinburne, J.E. | Syvanen, A.C. | Tozaki, T. | Valberg, S.J. | Vaudin, M. | White, J.R. | Zody, M.C. | , | Lander, E.S. | Lindblad-Toh, K. | Broad Institute [Cambridge] ; Harvard University-Massachusetts Institute of Technology (MIT) | Center for Human Genetic Research ; Massachusetts General Hospital [Boston] | Faculty of Veterinary Sciences ; The University of Sydney | Dipartimento di Genetica e Microbiologia ; Università degli Studi di Pavia [Italia] = University of Pavia [Italy] = Université de Pavie [Italie] (UNIPV) | Department of Medical Biochemistry and Microbiology ; Uppsala University | Dipartimento di Biologia ; Alma Mater Studiorum Università di Bologna = University of Bologna (UNIBO) | Maxwell H. Gluck Equine Research Center, Department of Veterinary Science ; University of Kentucky (UK) | University of Adelaide | University of Tampa | Helmholtz Centre for Infection Research (HZI) | Institute of Animal Breeding and Genetics ; University of Veterinary Medecine Hannover | 45 Monterey Drive | Institute of Genetics ; Universität Bern = University of Bern = Université de Berne (UNIBE) | Veterinary Genetics Laboratory ; University of California (UC) | The Wellcome Trust Sanger Institute [Cambridge] | Cornell University [New York] | Royal Veterinary College | Génétique Animale et Biologie Intégrative (GABI) ; Institut National de la Recherche Agronomique (INRA)-AgroParisTech | Equine Research Institute ; Japan Racing Association | Animal Genomics Laboratory, School of Agriculture, Food Science and Veterinary Medicine ; University College Dublin [Dublin] (UCD) | Genetic Information Research Institute | Department of Medical Sciences ; Uppsala University | Department of Animal Bredding and Genetics ; Swedish University of Agricultural Sciences = Sveriges lantbruksuniversitet (SLU) | Department of Computer Science ; University of Kentucky (UK) | College of Veterinary Medecine ; University of Minnesota [Twin Cities] (UMN) ; University of Minnesota System (UMN)-University of Minnesota System (UMN) | Population Health and Reproduction, School of Veterinary Medicine ; University of California (UC) | Department of Genetics and Microbiology ; Università degli studi di Bari Aldo Moro = University of Bari Aldo Moro (UNIBA) | San Diego Zoo's Institute for Conservation Research | College of Veterinary Medicine ; Texas A&M University System | Animal Health Trust (AHT) | Department of Molecular Genetics ; Laboratory of Racing Chemistry | College of Veterinary Medicine ; University of Minnesota [Twin Cities] (UMN) ; University of Minnesota System (UMN)-University of Minnesota System (UMN) | Department of Biology ; Howard Hughes Medical Institute (HHMI)-Massachusetts Institute of Technology (MIT)
We report a high-quality draft sequence of the genome of the horse (Equus caballus). The genome is relatively repetitive but has little segmental duplication. Chromosomes appear to have undergone few historical rearrangements: 53% of equine chromosomes show conserved synteny to a single human chromosome. Equine chromosome 11 is shown to have an evolutionary new centromere devoid of centromeric satellite DNA, suggesting that centromeric function may arise before satellite repeat accumulation. Linkage disequilibrium, showing the influences of early domestication of large herds of female horses, is intermediate in length between dog and human, and there is long-range haplotype sharing among breeds.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Institut national de la recherche agronomique