New avian paramyxoviruses type I strains identified in Africa provide new outcomes for phylogeny reconstruction and genotype classification
2013
Servan de Almeida, Renata | Hammoumi, Saliha | Gil, Patricia | Briand, François-Xavier | Molia, Sophie | Gaidet, Nicolas | Cappelle, Julien | Chevalier, Véronique | Balança, Gilles | Traore, Abdallah | Grillet, Colette | Maminiaina, Olivier Fridolin | Guendouz, Samia | Dakouo, Marthin | Samake, Kassim | Bezeid, Ould El Mamy | Diarra, Abbas | Chaka, Hassen | Goutard, Flavie | Thompson, Peter | Martinez, Dominique | Jestin, Véronique | Albina, Emmanuel | Contrôle des maladies animales exotiques et émergentes (UMR CMAEE) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA) | Laboratoire de Ploufragan - Plouzané ; Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES) | Virologie, Immunologie, Parasitologie Avaires et Cunicoles (VIPAC) ; Laboratoire de Ploufragan-Plouzané-Niort [ANSES] ; Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES) | Animal et gestion intégrée des risques (UPR AGIRs) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad) | Laboratoire Central Vétérinaire [Bamako, Mali] | Centre National de Recherche Appliquée au Développement Rural (FOFIFA) | Centre National d’Elevage et de Recherches Vétérinaires (CNERV) | Animal Health | Fac Vet Sci ; The University of Sydney | French Ministry of Foreign Affairs (MAE) [GRIPAVI 2006-26]; EU network of excellence [EPIZONE (016236)]
International audience
اظهر المزيد [+] اقل [-]إنجليزي. Newcastle disease (ND) is one of the most lethal diseases of poultry worldwide. It is caused by an avian paramyxovirus 1 that has high genomic diversity. In the framework of an international surveillance program launched in 2007, several thousand samples from domestic and wild birds in Africa were collected and analyzed. ND viruses (NDV) were detected and isolated in apparently healthy fowls and wild birds. However, two thirds of the isolates collected in this study were classified as virulent strains of NDV based on the molecular analysis of the fusion protein and experimental in vivo challenges with two representative isolates. Phylogenetic analysis based on the F and HN genes showed that isolates recovered from poultry in Mali and Ethiopia form new groups, herein proposed as genotypes XIV and sub-genotype VIf with reference to the new nomenclature described by Diel's group. In Madagascar, the circulation of NDV strains of genotype XI, originally reported elsewhere, is also confirmed. Full genome sequencing of five African isolates was generated and an extensive phylogeny reconstruction was carried out based on the nucleotide sequences. The evolutionary distances between groups and the specific amino acid signatures of each cluster allowed us to refine the genotype nomenclature.
اظهر المزيد [+] اقل [-]المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Institut national de la recherche agronomique