Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evolution
2019
Hill, Jason | Rastas, Pasi | Hornett, Emily A. | Neethiraj, Ramprasad | Clark, Nathan | Morehouse, Nathan | de La Paz Celorio-Mancera, Maria | Cols, Jofre Carnicer | Dircksen, Heinrich | Meslin, Camille | Keehnen, Naomi | Pruisscher, Peter | Sikkink, Kristin | Vives, Maria | Vogel, Heiko | Wiklund, Christer | Woronik, Alyssa | Boggs, Carol L. | Nylin, Sören | Wheat, Christopher W. | Stockholm University | Department of Medical Biochemistry and Microbiology ; Uppsala University | Institute of Biotechnology ; Albanova University Center-KTH Royal Institute of Technology [Stockholm] (KTH) | Department of Zoology ; University of Cambridge [UK] (CAM) | Institute of Integrative Biology (IBZ) ; Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich) | Liverpool School of Tropical Medicine (LSTM) | Department of Computational and Systems Biology ; University of Pittsburgh (PITT) ; Pennsylvania Commonwealth System of Higher Education (PCSHE)-Pennsylvania Commonwealth System of Higher Education (PCSHE) | Department of Biological Sciences ; The Open University [Milton Keynes] (OU) | Universitat de Barcelona (UB) | Universitat Autònoma de Barcelona = Autonomous University of Barcelona = Universidad Autónoma de Barcelona (UAB) | Institut d'écologie et des sciences de l'environnement de Paris (iEES Paris) ; Institut National de la Recherche Agronomique (INRA)-Sorbonne Université (SU)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS) | Department of Ecology, Evolution and Behavior (EEB) ; University of Minnesota [Twin Cities] (UMN) ; University of Minnesota System (UMN)-University of Minnesota System (UMN) | Department of Biology ; The University of Mississippi [Oxford] | Department of Entomology ; Michigan State University [East Lansing] ; Michigan State University System-Michigan State University System | New York University ; New York University [New York] (NYU) ; NYU System (NYU)-NYU System (NYU) | Department of Biological Sciences ; University of South Carolina [Columbia] | Funding was provided by the Swedish Research Council [VR grant numbers 2012-3715 (to S.N.), 2010-5341 (to S.N.), and 621-2012-4001 (to C.W.W.)], the Academy of Finland [grant number 131155 (to C.W.W.)], the Knut and Alice Wallenberg Foundation (grant number 2012.0058), and MINECO-FEDER [project number CGL2016- 78093-R (to J.C.C.)]
International audience
اظهر المزيد [+] اقل [-]إنجليزي. Chromosome evolution presents an enigma in the mega-diverse Lepidoptera. Most species exhibit constrained chromosome evolution with nearly identical haploid chromosome counts and chromosome-level gene collinearity among species more than 140 million years divergent. However, a few species possess radically inflated chromosomal counts due to extensive fission and fusion events. To address this enigma of constraint in the face of an exceptional ability to change, we investigated an unprecedented reorganization of the standard lepidopteran chromosome structure in the green-veined white butterfly (Pieris napi). We find that gene content in P. napi has been extensively rearranged in large collinear blocks, which until now have been masked by a haploid chromosome number close to the lepidopteran average. We observe that ancient chromosome ends have been maintained and collinear blocks are enriched for functionally related genes suggesting both a mechanism and a possible role for selection in determining the boundaries of these genome-wide rearrangements.
اظهر المزيد [+] اقل [-]المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Institut national de la recherche agronomique