Effects of zinc pyrithione on biochemical parameters of the freshwater Asian clam Corbicula fluminea
2018
Nogueira A.F. | Pereira J.L. | Antunes S.C. | Gonçalves F.J.M. | Nunes B. | CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental
Zinc pyrithione (ZnPT) is an organometallic biocide with bactericide, algaecide, and fungicide activity. Considering this biological activity, ZnPT has been used in anti-fouling paints, and also in human therapeutics and cosmetics, in shampoos to treat dandruff and seborrhoea. Despite its potential uses and consequent presence in the aquatic environment, the ecotoxicological effects of ZnPT are poorly understood. This work aims to characterise the effects of ZnPT in biochemical parameters of the Asian clam, one of the most invasive bivalves known for its biofouling action in hydro-dependent industries, using a classical (LC50 determination) and a biomarker-based approach (quantification of the activities of catalase, GSTs, and acetylcholinesterase, and also the muscle glycogen content). The here determined LC50-96 h for zinc pyrithione was 2.17 mg/L. ZnPT caused significant increases in the activity of catalase and of cholinesterases. These findings evidence the pro-oxidative effects caused by the metabolism of ZnPT. Despite the absence of clear effects, it is important to stress that the presence of ZnPT in the wild is usually accompanied by other pyrithiones, whose co-existence can contribute to the exertion of considerable toxic effects. © 2018 Elsevier
اظهر المزيد [+] اقل [-]Bruno Nunes was hired through the Investigator FCT program (IF/01744/2013). Joana L. Pereira and Sara Antunes are recipients of individual post-doctoral grant ( SFRH/BPD/101971/2014 and SFRH/BPD/109951/2015 , respectively) by the Portuguese Foundation for Science and Technology (FCT) . Thanks also due to CESAM (UID/AMB/50017) for financial support and FCT through national funds and co-funding FEDER , within the PT2020 Partnership Agreement.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Universidade do Porto