BIORESONANCE METHOD OF ESTIMATION METABOLIC FUNCTION OF THE LIVER IN DOGS

The study was conducted on 35 dogs of various breeds. In the blood of experimental animals, the number of formed elements was considered, the hemoglobin, total protein, protein fractions, urea, uric acid, ammonia, amino nitrogen, creatinine, glucose, glycogen, pyruvic acid and lactic acid concentrations, cholesterol, triacylglycerols were determined. Two groups of dogs were formed: the control group – without changes in the metabolic function of the liver and the experimental – with a decrease in this function. Then we used the program of individual bioresonance testing Parkes-D device for a comprehensive assessment of the state of organs and systems of animals, the electrical conductivity of biologically active points was determined with diagnostic markers and the efficiency and informativeness of the bioresonance method were compared. The decrease in the functional state of the metabolic function of the liver in dogs is characterized by a lower number of red blood cells 12.0–16.9 % (p<0.01) and a hemoglobin content in the blood 14.8–16.5 % (p<0.05), a significantly higher number of leukocytes 48.6–51.9 % (p<0.001) and a high content of total bilirubin in the blood 56.0–66.9 % (p<0,001). A decrease in the metabolism of proteins, fats and carbohydrates in the body of dogs were detected, in particular, a lower content of total protein was found 10.5 % (p<0.05) and albumin 13.1 % (p<0,05), higher content of amino nitrogen 11.7 %, urea 69.4 % (p<0.001) and ammonia 22.0 % (p<0.01), a decrease in blood urea content 18.2 % (p<0,05), ammonia 9.8 % (p<0.05) and uric acid 11.9 % (p<0.05), a higher content of pyruvate 33.3 % (p<0.01) and lactate by 22.2 % (p<0.01), and the content of triacylglycerols, phospholipids and cholesterol was lower by 16.1 % (p<0.05), 21.4 % (p<0.05) and 13,0 % (p<0.05). During the study of the bioresonance with the help of markers of the functional state of the liver with diagnostic complex “Parkes-D” it was determined that out of 35 dogs 14 had a decrease in their metabolic function, and the data of 13 dogs correspond with laboratory blood values. It has been established that the use of functional testing by the hardware-software diagnostic complex "Parkes-D" allows to determine changes in the metabolic function of the liver with a probability up to 91.4 %.