A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients
2023
Lauren A. Peters | Joshua R. Friedman | Aleksandar Stojmirovic | Jacob Hagen | Sander Houten | Tetyana Dodatko | Mariana P. Amaro | Paula Restrepo | Zhi Chai | J. Rodrigo Mora | Holly A. Raymond | Mark Curran | Radu Dobrin | Anuk Das | Huabao Xiong | Eric E. Schadt | Carmen Argmann | Bojan Losic
Longitudinal changes in gene expression, splicing patterns and adaptive immune repertoire in murine models of colitis are examined and associated with histologic inflammation in mice and in patients with inflammatory bowel disease.
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