Antimicrobial Activity on <i>Streptococcus mutans</i> and <i>Enterococcus faecalis</i> of <i>Cyperus articulatus</i> Ethanolic Extracts
2024
Daniela Vieira de Castro Macambira | José Sousa de Almeida Júnior | Claudia Fernandes de Magalhães Silveira | Sandra Layse Ferreira Sarrazin | Tânia Mara Pires Moraes | Bruno Alexandre da Silva | Antonio Humberto Hamad Minervino | Waldiney Pires Moraes | Lauro Euclides Soares Barata
Oral diseases are one of the biggest public health problems worldwide, caused by opportunistic pathogens such as <i>Streptococcus mutans</i> and <i>Enterococcus faecalis</i>. <i>Cyperus articulatus</i> (priprioca) is a plant conventionally used in traditional medicine in the Amazon region. However, little is known about the possible dentistry-related uses of extracts from the rhizomes and solid waste generated by the extraction of essential oils from this vegetable. This study aimed to investigate the chemical composition of volatile compounds and antimicrobial activity through the Minimum Inhibitory Concentration test (MIC and assessment of the toxicity by Hens Egg Test-Chorion Allantoic Membrane (HET-CAM) of the ethanolic extracts from <i>Cyperus articulatus</i> intact rhizomes and solid waste. We identified sesquiterpenes as the main constituents, strong antimicrobial activity of the ethanolic extract of intact rhizomes against <i>S. mutans</i> (MIC = 0.29 mg/mL), moderate antimicrobial activity against <i>E. faecalis</i> of the extract obtained from the solid waste (MIC = 1.17 mg/mL), and absence of toxicity for both tested extracts. The absence of irritation and the antibacterial activity of the ethanolic extract from <i>C. articulatus</i> rhizomes and solid waste reveal its potential for use in the alternative control of bacteria that cause oral infections and may present economic viability as a raw material for dental products.
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