HEMATOLOGICAL AND OXIDATIVE STATUS PARAMETERS IN DOMESTIC DOGS NATURALLY INFESTED BY RHIPICEPHALUS SP.
2020
Rosa Kebbi | Omar Besseboua | Melaaz Belhadj-Kebbi | Lila Hassissen | Abdelhanine Ayad
The present study was aimed to evaluate hematological and oxidative stress parameters in domestic dogs infested naturally (n=10) by Rhipicephalus sp. to compare with non-infested dogs (n=10). All blood samples were collected from brachial vein into tubes EDTA for the hematological analysis such as red blood cells (RBCs), white blood cells (WBCs), hemoglobin (HGB) and platelets (PLT). Serum was rapidly separated after centrifugation and stored at -20 °C until it was used for malondialdehyde (MDA) and 2,2’-Azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) inhibition measurements. HGB in non-infested dogs was significantly higher than in infested dogs (P<0.05). There was not a significant difference in RBCs, WBCs and PLT between bothgroups (P>0.05). The mean of MDA concentration was high in infested dogs. (0.92±0.62 nmol/ml) compared to non-infested dogs (0.75±0.25 nmol/ml). On the other hand, the percentage of ABTS inhibition was similar in both groups (P=0.71). High tick number seems significantly affected WBCs (P<0.0001) and HGB (P<0.001) in infested dogs. Concerning oxidative status, there is no significant differences (P>0.05) between low and high infested dogs neither in the amount of MDA nor in the ABTS inhibition. In conclusion, infested dogs induce RBCs alterations, which coincides with the oxidative damage, as evidenced by MDA serum levels. Also, there was a relationship between the tick number in infested dogs and the hematological parameters.
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