Seronegative <i>Myasthenia Gravis</i> with Concomitant SARS-CoV-2 Infection in a Dog
2022
Mihai Musteata | Denis-Gabriel Borcea | Andreea Despa | Raluca Ștefănescu | Larisa Ivănescu | Luminița Diana Hrițcu | Radu Andrei Baisan | Radu Lăcătuș | Gheorghe Solcan
<i>Myasthenia gravis</i> (MG) is a disorder of neuromuscular transmission affecting the neuromuscular junction. The majority of cases involve an autoimmune attack against AChR, but a limited number of patients are seronegative for AChR antibodies. Viral infection is incriminated as a trigger for MG occurrence, and in a limited number of reports, infection with SARS-CoV-2 was found to be associated with MG expression in humans. In this report, we describe case of seronegative generalized MG in a 2-year-old crossbred female dog associated with SARS-CoV-2 infection due to close exposure to an infected owner.
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