文冠果壳中总皂苷和总黄酮的抗氧化活性"Antioxidant activity of total saponins and total flavonoids from Xanthoceras sorbifolia Bunge shells"
2024
刘荣徽，魏媛，刘超，赵光鸿，杨洋，刘玉冰，汪甜甜，王珊，史高峰，王国英LIU Ronghui, WEI Yuan, LIU Chao, ZHAO Guanghong, YANG Yang,
旨在为文冠果壳资源的综合利用提供参考，通过DPPH自由基、超氧阴离子自由基、羟自由基及脂质过氧自由基清除能力研究文冠果壳总皂苷和总黄酮的抗氧化活性,并分析了抗氧化活性与构效关系。结果表明：文冠果壳总皂苷和总黄酮均具有一定的DPPH自由基、超氧阴离子自由基、羟自由基及脂质过氧自由基清除能力，且文冠果壳总黄酮对4种自由基的清除能力均高于文冠果壳总皂苷；构效关系分析表明，文冠果壳总皂苷和总黄酮抗氧化活性差异与其化学结构有关。综上，从文冠果壳中提取总黄酮，并将其作为天然抗氧化剂进行开发，有助于提高文冠果壳资源的综合利用价值。 Aiming to provide a reference for the comprehensive utilization of Xanthoceras sorbifolia Bunge shells resources,the antioxidant activities of total saponins and total flavonoids extracted from Xanthoceras sorbifolia Bunge shells were studied through their scavenging capacities against DPPH free radicals, superoxide anion radicals, hydroxyl radicals, and lipid peroxide radicals. The relationship between antioxidant activity and structure-activity of the compounds extracted from Xanthoceras sorbifolia Bunge shells was analyzed.The results indicated that both total saponins and total flavonoids from Xanthoceras sorbifolia Bunge shells had certain scavenging abilities against these four types of free radicals, with the total flavonoids exhibiting higher scavenging capacities than the total saponins for all tested radicals.The structure-activity relationship analysis indicated that the differences in antioxidant activity between the total saponins and total flavonoids from Xanthoceras sorbifolia Bunge shells were related to their chemical structures.In conclusion, extracting total flavonoids from Xanthoceras sorbifolia Bunge shells and developing them as natural antioxidants can help enhance the comprehensive utilization value of Xanthoceras sorbifolia Bunge shells resources.
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