THE ENANTIOSELECTIVE SYNTHESIS OF NEW ANTY-($S$)-$\beta$-OXY-SUBSTITUTED TYROSINES
2011
Saghiyan, A.S. | Dadayan, A.S. | Dadayan, S.A.
Reactions of asymmetric aldol condensation of Nill complex of the Shiff base of glycine and chiral auxiliary (S)-2-N-[N’-(2-fluorobenzylprolyl)amino]benzophe-none Nill-(S)-2-FBPB-Gly by benzaldehydes 4-CH3O-C6H4CHO, 3-Br-4-CH3O-C6H3CHO were investigated. As a results the synthesis of new enantiomericaly pure phenyl substituted derivatives of Tyrozine (2S, 3S)-β-oxy-4-OMe-Tyr (ee 91%) and (2S, 3S)-β-oxy-3-Br-Tyr (ee 92%) is carried out.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Yerevan State University