Regulatory assessment of in vitro skin corrosion and irritation data within the European framework: Workshop recommendations

accuracy alternative methods animal animal testing alternatives animalia animals assessment berlin biotechnology caustics chemical analysis chemicals classification corrosion countries development ec ecology effects epidermis eu europe european union evaluation experiments feasibility studies france germany guidelines health in vitro information italy labelling law legislation management materials methods model oecd organization pharmacology products protection public health publications rat registration restriction risk risk assessment safety skin stakeholder standard standards state statistics strategies substances switzerland system testing tests time toxicity toxicology transport usa