Molecular epidemiology of Brucella genotypes in patients at a major hospital in central Peru
2009
Nöckler, K. | Maves, R. | Cepeda, D. | Draeger, A. | Mayer-Scholl, A. | Chacaltana, J. | Castaneda, M. | Espinosa, B. | Castillo, R. | Hall, E. | Al Dahouk, S. | Gilman, R. H. | Cabeza, F. | Smits, H. L.
ألمانية. The multiple-locus variable-number repeat analysis of 90 human Brucella melitensis isolates from a large urban area in central Peru revealed variations at 4 (Bruce07, Bruce09, Bruce18, and Bruce42) out of 16 loci investigated, of which 1 (Bruce42) also is used for species identification. Ten genotypes were identified, separated by the number of Bruce42 repeats into two groups that may have distinct phenotypic characteristics. Whereas genotypes with five or six Bruce42 repeats were cultured mainly from adult patients, genotypes with three Bruce42 repeats were isolated from children and young adolescents as well as from adults. In addition, the isolates with three Bruce42 repeats were obtained more often from patients with splenomegaly (P = 0.02) or hepatomegaly (P = 0.006). An annual variation in the diversity of genotypes was observed, possibly reflecting changes in sources of fresh dairy products, supply routes to city shops and markets, and the movement of infected dairy goat herds
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
الناشر American Society for Microbiology (ASM) ; PubMed Central
الرقم التسلسلي المعياري الدولي (ردمد) 0095-1137 | 1098-660Xتم تزويد هذا السجل من قبل German Federal Institute for Risk Assessment