The atypical soluble guanylyl cyclase subunit Gyc89Db does not control neuroepithelial proliferation in Drosophila larval brain
2024
Rosas, Mariel | Cantera, Rafael | Prieto, Daniel
We investigated the role of oxygen-sensing atypical guanylyl cyclase subunit Gyc89Db in the developing brain. Despite its expression in the hypoxic neuroepithelium of the larval optic lobe of Drosophila, loss-of-function mutants and ectopic expression did not alter neuroepithelial cell number or proliferation. Notably, while ectopic expression of Gyc89Db increases optic lobe volume and neuroblast numbers, our negative results suggest that these effects manifest earlier in development without persistent alteration of the neuroepithelium, through mechanisms that might be independent of neuroepithelial proliferation.
اظهر المزيد [+] اقل [-]Dirección Nacional de Innovación Ciencia y Tecnología - Ministerio de Educación y Cultura
اظهر المزيد [+] اقل [-]Agencia Nacional de Investigación e Innovación
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Instituto de Investigaciones Biológicas Clemente Estable