THE EFFECT OF COCONUT OIL EXTRACT ON FULL THICKNESS WOUND HEALING ON THE FEMALE RABBIT

Our experiment used ( 12 ) female rabbits divided into three groups every group have ( 4 ) rabbits were studied for their wound healing properties in the form of ointment, using one type wound models (full thickness incisional wounds) .The ointments of oil extraction of coconut were applied in concentration 5mg used in the present study. The pathological examination into 3rd days of treated wound shows, there are a little hemorrhagic area ,inflammatory cells are more in number, ,plasma cells are high in numbers and very little neutrophils ,cloudy swelling in skin cells ,and hemorrhages into dermis compared with a control wound that show first stage of healing presence of hemorrhagic area and congestion ,slight inflammatory cells infiltration neutrophils, collagen fibers , and skin cells . While after 7th days the treated wound shows absence of hemorrhagic area , presence of inflammatory cells especially macrophage cells ,plasma cells . Absence of neutrophils, granulation tissue and growth of layer, new blood vessels and bundles of collagens and re-epithelization compared with a control wound that showed a clot into hemorrhagic area , granulation tissue and growth of skin layers , bundles of collagens, vacuolated skin cells, epithelial cells, plasma cells, macrophage cells, and neutrophils debris . After 14th days the treated wounds show debris of granulation tissue, excessive collagen bundles, with epithelial cells remodeling and macrophages found in the area while control wound showed little hemorrhagic area ,the stratum cranium formation , absorption of granulation tissue ,and vacuolated skin cells . There is a little macrophage into the margin of the wound. Aimed of my study to study the effect of coconut oil extract on the healing of skin wounds .The work of this research into Pathology and poultry diseases department -Veterinary Medicine college .