Antimicrobial Diterpenoids of Wedelia trilobata (L.) Hitchc
2016
Shi-Fei Li | Jia-Yin Ding | Ya-Ting Li | Xiao-Jiang Hao | Shun-Lin Li
Continued interest in the metabolites of Wedelia trilobata (L.) Hitchc, a notoriously invasive weed in South China, led to the isolation of twenty-six ent-kaurane diterpenoids, including seven new ones 1–7. Their structures and relative configuration were elucidated on the basis of extensive spectroscopic analysis, including 1D- and 2D-NMR experiments. The antimicrobial activities of all isolated diterpenoids were evaluated against a panel of bacteria and fungi.
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