Lavandula pedunculata subsp. atlantica: A Multifunctional Essential Oil for Potentially Combating Microbial Infections and Inflammatory Processes
2025
Giusy Castagliuolo | Natale Badalamenti | Vincenzo Ilardi | Gianfranco Fontana | Dario Antonini | Mario Varcamonti | Maurizio Bruno | Anna Zanfardino
The genus Lavandula L., belonging to the Lamiaceae family, contains about forty species with a distribution that mainly extends in the Mediterranean basin from the North Atlantic to the Middle East. Due to their excellent biological properties, the aerial parts and flowers of Lavandula peduncolata ssp. have been utilized in traditional medicine in Morocco and western Europe. This paper investigated the chemical composition and antibacterial activities as well as the antibiofilm and antioxidant activities of the essential oil (EO) obtained from the pre-flowering aerial parts of Lavandula pedunculata subsp. atlantica collected in Morocco. The chemical composition of the EO, obtained by classic hydrodistillation, showed by GC-MS analysis the presence of a large amount of oxygenated monoterpene compounds. The main constituents of the EO were camphor (27.8%), camphene (10.9%), fenchone (10.6%), and eucalyptol (8.5%). The EO has been evaluated for its antimicrobial, antibiofilm, antioxidant and anti-inflammatory properties, showing promising activity against both Gram-positive and Gram-negative strains. These findings highlight the potential of Lavandula EO in combating infections caused by Streptococcus mutans and Streptococcus oralis (oral diseases), Staphylococcus aureus (skin infections), Escherichia coli and Shigella sonnei (gastrointestinal and urinary infections). In addition, although the EO showed no evident effects on cell viability in eukaryotic epithelial cells, it exhibited promising effects on anti-inflammatory properties.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
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