The nutritional value and organoleptic evaluation of rabbit showed that the meat of rabbits raised on the eco-farm and in the modular rabbit house did not differ from each other and had the best nutritional and biochemical qualities, indicating the prospects of using modular farms to produce high quality products. A high percentage of fresh meat yield was found – 53.6 and 53.9% in rabbits raised in the module and on the eco-farm. Rabbit carcasses from the module had more fat by 1.1% and slightly enlarged kidneys due to the peculiarity of the equipment. Changes in the chemical composition – a slight increase in moisture and fat content (by 0.2%) in the meat, which was obtained by raising in the modular rabbit house compared to the meat of rabbits raised on the eco-farm – were founded. At the same time there was 0.3% less protein and 0.1% less sol. In general, the difference in chemical composition was insignificant, which indicated the identity of the analyzed samples. The organoleptic characteristics of rabbit meat in the carcass at slaughter and after heat treatment were studied. Muscle consistency was dense, elastic, when pressed the formed hole was quickly leveled; fat was dense. The aroma was specific for fresh meat. All samples taken from sampling of “Hy-plus” hybrid rabbits raised in the modular rabbit house and those raised on the eco-farm had the highest scores. The studied samples by organoleptic evaluation did not differ from each other and corresponded to high quality rabbit. Carcasses of hybrids in the experimental groups had a high content of saturated, monounsaturated and polyunsaturated fatty acids and the lowest content of cholesterol (0.04 g/100 g). The difference between the amino acid composition of meat and the lipid composition of fat in the study groups was insignificant

The nutritional value and organoleptic evaluation of rabbit showed that the meat of rabbits raised on the eco-farm and in the modular rabbit house did not differ from each other and had the best nutritional and biochemical qualities, indicating the prospects of using modular farms to produce high quality products. A high percentage of fresh meat yield was found – 53.6 and 53.9% in rabbits raised in the module and on the eco-farm. Rabbit carcasses from the module had more fat by 1.1% and slightly enlarged kidneys due to the peculiarity of the equipment. Changes in the chemical composition – a slight increase in moisture and fat content (by 0.2%) in the meat, which was obtained by raising in the modular rabbit house compared to the meat of rabbits raised on the eco-farm – were founded. At the same time there was 0.3% less protein and 0.1% less sol. In general, the difference in chemical composition was insignificant, which indicated the identity of the analyzed samples. The organoleptic characteristics of rabbit meat in the carcass at slaughter and after heat treatment were studied. Muscle consistency was dense, elastic, when pressed the formed hole was quickly leveled; fat was dense. The aroma was specific for fresh meat. All samples taken from sampling of “Hy-plus” hybrid rabbits raised in the modular rabbit house and those raised on the eco-farm had the highest scores. The studied samples by organoleptic evaluation did not differ from each other and corresponded to high quality rabbit. Carcasses of hybrids in the experimental groups had a high content of saturated, monounsaturated and polyunsaturated fatty acids and the lowest content of cholesterol (0.04 g/100 g). The difference between the amino acid composition of meat and the lipid composition of fat in the study groups was insignificant

As the requirements for the quality of agricultural machinery and its working conditions increase, so do the demands on its maintainability, in particular its reliability. Failure for technical reasons or due to any external factors will result in the non-achievement of the goals set, and thus in a loss of performance. Today, as a rule, there is an insufficient level of reliability of agricultural equipment during operation, and this issue receives special attention in the territories that are located in the front-line zone in the east of Ukraine in the Donetsk and Luhansk regions. This is caused by both design solutions and imperfect models that are used during projecting. In addition, external factors that can significantly affect production activities are not taken into account. These include climatic conditions, natural disasters, personnel readiness, i.e. the human factor, as well as the factor of the consequences of an armed conflict. Therefore, the purpose of the article is to offer a mathematical model for assessing the reliability of agricultural machinery, taking into account the military factor in the front-line territory. The authors provide an analytical expression of the mathematical model for assessing the reliability of agricultural machinery, taking into account the influence of external military factors. This issue is gaining special attention in the front-line territories in eastern Ukraine, where a significant part of the acreage is also located. The proposed mathematical model, in contrast to the previous ones, will allow taking into account the wear and time-related deterioration of components of agricultural machinery, as well as external military factors (damage to equipment and personnel, damage due to collision with munitions, etc.). This mathematical model can be used to set the uptime requirements for agricultural machinery in a more reasonable manner and thereby increase its productive performance. During the research, methods of probability theory were used at the stage of determining the necessary probabilities of trouble-free operation of agricultural machinery, as well as methods of queuing theory, reliability theory of technical systems and mathematical modelling when determining the maintenance time of agricultural machinery samples for failure under various conditions of its application

As the requirements for the quality of agricultural machinery and its working conditions increase, so do the demands on its maintainability, in particular its reliability. Failure for technical reasons or due to any external factors will result in the non-achievement of the goals set, and thus in a loss of performance. Today, as a rule, there is an insufficient level of reliability of agricultural equipment during operation, and this issue receives special attention in the territories that are located in the front-line zone in the east of Ukraine in the Donetsk and Luhansk regions. This is caused by both design solutions and imperfect models that are used during projecting. In addition, external factors that can significantly affect production activities are not taken into account. These include climatic conditions, natural disasters, personnel readiness, i.e. the human factor, as well as the factor of the consequences of an armed conflict. Therefore, the purpose of the article is to offer a mathematical model for assessing the reliability of agricultural machinery, taking into account the military factor in the front-line territory. The authors provide an analytical expression of the mathematical model for assessing the reliability of agricultural machinery, taking into account the influence of external military factors. This issue is gaining special attention in the front-line territories in eastern Ukraine, where a significant part of the acreage is also located. The proposed mathematical model, in contrast to the previous ones, will allow taking into account the wear and time-related deterioration of components of agricultural machinery, as well as external military factors (damage to equipment and personnel, damage due to collision with munitions, etc.). This mathematical model can be used to set the uptime requirements for agricultural machinery in a more reasonable manner and thereby increase its productive performance. During the research, methods of probability theory were used at the stage of determining the necessary probabilities of trouble-free operation of agricultural machinery, as well as methods of queuing theory, reliability theory of technical systems and mathematical modelling when determining the maintenance time of agricultural machinery samples for failure under various conditions of its application

Bringing to safe health standards and maintaining the basic parameters of the air (microclimate) in the premises for various purposes within the established limits with a high level of efficiency, pro-vides an opportunity to solve the problem of national importance – public health and the necessary environmental characteristics. The purpose of the study is to develop technology and foundations for the construction of universal systems of automated high-quality air purification in rooms for various purposes. Methods of analysis, synthesis, mathematical modelling, and engineering calculations were used in the research process. The technology, composition, and structure of universal systems for au-tomated cleaning and maintenance of the required indoor air quality, which provides automatic control of air parameters, have been developed. The composition and features of software and hardware are substantiated, the method of engineering calculation, structure of air purification system is developed and its technical parameters are defined. The synergetic effects in the implementation of air purification, which are achieved through a comprehensive, consistent with the procedures and pro-cesses of sequential parallel processing of injected and filtered air, have been investigated and proved. Developed technology and systems provide the ability to purify large volumes of air at high speed and quality in rooms with different levels of mechanical contamination, microflora, other harmful impurities, including microorganisms, allergens, dangerous viruses that cause infections with pathogens diseases characterised by mass and high rate of spread, such as COVID-19. For the first time, the problem of creation of energy-efficient high power systems of complex air purification for industrial premises of large sizes, which are 2.5-4 times more effective on all basic indicators in com-parison with the best analogues has been solved

Bringing to safe health standards and maintaining the basic parameters of the air (microclimate) in the premises for various purposes within the established limits with a high level of efficiency, pro-vides an opportunity to solve the problem of national importance – public health and the necessary environmental characteristics. The purpose of the study is to develop technology and foundations for the construction of universal systems of automated high-quality air purification in rooms for various purposes. Methods of analysis, synthesis, mathematical modelling, and engineering calculations were used in the research process. The technology, composition, and structure of universal systems for au-tomated cleaning and maintenance of the required indoor air quality, which provides automatic control of air parameters, have been developed. The composition and features of software and hardware are substantiated, the method of engineering calculation, structure of air purification system is developed and its technical parameters are defined. The synergetic effects in the implementation of air purification, which are achieved through a comprehensive, consistent with the procedures and pro-cesses of sequential parallel processing of injected and filtered air, have been investigated and proved. Developed technology and systems provide the ability to purify large volumes of air at high speed and quality in rooms with different levels of mechanical contamination, microflora, other harmful impurities, including microorganisms, allergens, dangerous viruses that cause infections with pathogens diseases characterised by mass and high rate of spread, such as COVID-19. For the first time, the problem of creation of energy-efficient high power systems of complex air purification for industrial premises of large sizes, which are 2.5-4 times more effective on all basic indicators in com-parison with the best analogues has been solved

One of the strategic areas for the development of modern agriculture is the use of ecologised fertiliser systems composed based on the straw of agricultural crops with the addition of microbiological, humus or chelated fertilisers. This will allow restoring natural resources and getting environmentally friendly products. The purpose of the research was to study the effect of ecologised fertiliser systems on the physical and chemical processes and nitrogen regime of grey forest soil, the development of bio-productivity of winter wheat, and the content of basic microelements in grain. The following methods were used in the research: field, laboratory-analytical, mathematical-statistical. Application of N30P45K45 against the background of pea straw with the addition of a biostimulator and humus fertiliser mostly demonstrated modern approaches to technologies for managing the fertility of grey forest soils based on the principles of environmental safety and resource conservation. Such a fertiliser system provided alkalinisation of the soil solution, optimisation of the Ca2+ and Mg2+ content, improvement of the soil nitrogen regime. Under such conditions, optimal parameters of the production process elements (the number and mass of grains in the head) were formed. The most effective in the processes of accumulation of microelements was the organo-mineral system of the following composition: pea straw + N30R45K45 + chelated fertiliser. No excess of the maximum permissible concentration for Cu, Zn, Mn, or Fe was detected. Thus, to harmonise the ecological and productive functions of grey forest soil in the winter wheat cultivation system, a combination of alternative agriculture, which consists in reducing the use of mineral fertilisers, and partial biologisation, is considered promising. This is a way to optimise soil fertility and bio-productivity

One of the strategic areas for the development of modern agriculture is the use of ecologised fertiliser systems composed based on the straw of agricultural crops with the addition of microbiological, humus or chelated fertilisers. This will allow restoring natural resources and getting environmentally friendly products. The purpose of the research was to study the effect of ecologised fertiliser systems on the physical and chemical processes and nitrogen regime of grey forest soil, the development of bio-productivity of winter wheat, and the content of basic microelements in grain. The following methods were used in the research: field, laboratory-analytical, mathematical-statistical. Application of N30P45K45 against the background of pea straw with the addition of a biostimulator and humus fertiliser mostly demonstrated modern approaches to technologies for managing the fertility of grey forest soils based on the principles of environmental safety and resource conservation. Such a fertiliser system provided alkalinisation of the soil solution, optimisation of the Ca2+ and Mg2+ content, improvement of the soil nitrogen regime. Under such conditions, optimal parameters of the production process elements (the number and mass of grains in the head) were formed. The most effective in the processes of accumulation of microelements was the organo-mineral system of the following composition: pea straw + N30R45K45 + chelated fertiliser. No excess of the maximum permissible concentration for Cu, Zn, Mn, or Fe was detected. Thus, to harmonise the ecological and productive functions of grey forest soil in the winter wheat cultivation system, a combination of alternative agriculture, which consists in reducing the use of mineral fertilisers, and partial biologisation, is considered promising. This is a way to optimise soil fertility and bio-productivity

The establishment of rational terms and methods of mechanised pruning of apple trees on dwarf rootstocks determine the relevance of the subject under study. The purpose of this review is to highlight the current state and issues associated with tree pruning to improve the technology of growing and increasing the productivity of plantations yielding high-quality fruit with a rational period of mechanised pruning of apple trees on a dwarf rootstock. Proceeding from the analysed literature sources, this paper highlights the current state and development trends of horticulture. A gradual increase in apple production in Europe observed, but an important factor limiting the growth of fruit production is labour productivity accompanying the laborious processes of tree trimming and harvesting. The seasonal nature of work involving numerous skilled workers leads to a shortage of labour force in horticulture. With the increase in wages and the decrease in the number of workers in agricultural production, the introduction of elements of mechanised care for plantations, namely mechanised pruning of the crown, is gaining more significance. The solution to the problem is to improve modern technology of growing apple orchards, using mechanised pruning and the formation of fruit wall in particular. This will allow balancing the available number of employees involved in fruit cultivation and orchards area, and, if necessary, moving away from seasonal work. This paper investigates the specific features of the use and the influence of different periods of mechanised pruning, in particular in winter (0 BBCH), in the pink bud phase (59 BBCH), in early summer (74 BBCH), after harvesting (93 BBCH), and considers the mechanisms used for this purpose. The study proves the positive influence of this technology on improving setting illumination of the crown and the content of chlorophyll in the leaf, optimisation of growth processes with a considerable increase in the number of formed buds. The increase in yield and its marketable quality is accompanied by reducing the size of the fruit, the ripening time of which is somewhat delayed. However, the chemical composition and taste of the fruits are not inferior to the cultivation technology involving manual pruning. The practical significance of the obtained results is to improve the technology of growing apple trees using mechanised pruning and manual maintenance of the inter-tree space, which ensures a considerable reduction in the need for skilled manual labour and increases productivity

The establishment of rational terms and methods of mechanised pruning of apple trees on dwarf rootstocks determine the relevance of the subject under study. The purpose of this review is to highlight the current state and issues associated with tree pruning to improve the technology of growing and increasing the productivity of plantations yielding high-quality fruit with a rational period of mechanised pruning of apple trees on a dwarf rootstock. Proceeding from the analysed literature sources, this paper highlights the current state and development trends of horticulture. A gradual increase in apple production in Europe observed, but an important factor limiting the growth of fruit production is labour productivity accompanying the laborious processes of tree trimming and harvesting. The seasonal nature of work involving numerous skilled workers leads to a shortage of labour force in horticulture. With the increase in wages and the decrease in the number of workers in agricultural production, the introduction of elements of mechanised care for plantations, namely mechanised pruning of the crown, is gaining more significance. The solution to the problem is to improve modern technology of growing apple orchards, using mechanised pruning and the formation of fruit wall in particular. This will allow balancing the available number of employees involved in fruit cultivation and orchards area, and, if necessary, moving away from seasonal work. This paper investigates the specific features of the use and the influence of different periods of mechanised pruning, in particular in winter (0 BBCH), in the pink bud phase (59 BBCH), in early summer (74 BBCH), after harvesting (93 BBCH), and considers the mechanisms used for this purpose. The study proves the positive influence of this technology on improving setting illumination of the crown and the content of chlorophyll in the leaf, optimisation of growth processes with a considerable increase in the number of formed buds. The increase in yield and its marketable quality is accompanied by reducing the size of the fruit, the ripening time of which is somewhat delayed. However, the chemical composition and taste of the fruits are not inferior to the cultivation technology involving manual pruning. The practical significance of the obtained results is to improve the technology of growing apple trees using mechanised pruning and manual maintenance of the inter-tree space, which ensures a considerable reduction in the need for skilled manual labour and increases productivity

Rennet cheeses occupy an important place in the diets of the population of Ukraine. The technology of making cheeses depends on both the quality of raw materials and the quality of enzymes that are used to curdle milk. Therefore, the study of the effect of rennet enzymes obtained using advanced biotechnology on the transformation of milk protein and amino acids into a finished product is of scientific and practical importance. Considering the above, the purpose of this study was to investigate the amino acid composition of whey and cottage cheese for the use of various enzyme preparations. Three groups of samples (n=5) were formed to set up the experiment. Cow's milk for research was selected from clinically healthy cows during the milking period. In the control group of samples, rennet of microbial origin was used for milk clotting. In the first experimental group of samples, an enzyme preparation extracted from rennet of dairy calves was used according to the method of Yu.Ya. Svyrydenko. In the second experimental group, an enzyme preparation obtained by extraction of rennet enzymes according to the method of S.V. Merzlov was used. The content of amino acids in milk, whey, and cheeses was determined by capillary electrophoresis. Studying the milk used for the experiment, it was found that the content of amino acids (lysine, methionine + cystine, tryptophane, valine, leucine, isoleucine, phenylalanine + tyrosine, proline, serine, alanine, glycine, histidine, arginine, aspartic acid and glutamine) did not significantly differ from the typical indicators of milk obtained in central Ukraine. It was found that the use of rennet enzymes extracted according to the method of S.V. Merzlov is accompanied by a decrease in the content of amino acids in serum by an average of 15.9%

Rennet cheeses occupy an important place in the diets of the population of Ukraine. The technology of making cheeses depends on both the quality of raw materials and the quality of enzymes that are used to curdle milk. Therefore, the study of the effect of rennet enzymes obtained using advanced biotechnology on the transformation of milk protein and amino acids into a finished product is of scientific and practical importance. Considering the above, the purpose of this study was to investigate the amino acid composition of whey and cottage cheese for the use of various enzyme preparations. Three groups of samples (n=5) were formed to set up the experiment. Cow's milk for research was selected from clinically healthy cows during the milking period. In the control group of samples, rennet of microbial origin was used for milk clotting. In the first experimental group of samples, an enzyme preparation extracted from rennet of dairy calves was used according to the method of Yu.Ya. Svyrydenko. In the second experimental group, an enzyme preparation obtained by extraction of rennet enzymes according to the method of S.V. Merzlov was used. The content of amino acids in milk, whey, and cheeses was determined by capillary electrophoresis. Studying the milk used for the experiment, it was found that the content of amino acids (lysine, methionine + cystine, tryptophane, valine, leucine, isoleucine, phenylalanine + tyrosine, proline, serine, alanine, glycine, histidine, arginine, aspartic acid and glutamine) did not significantly differ from the typical indicators of milk obtained in central Ukraine. It was found that the use of rennet enzymes extracted according to the method of S.V. Merzlov is accompanied by a decrease in the content of amino acids in serum by an average of 15.9%

Nitrate filters are widely used in various sectors of the national economy for the purpose of stable degradation of nitrates without complex technological changes and control, as well as for obtaining, for practical use, water free from impurities of various polluting substances. The relevance of the stated research topic is determined by the wide use of filters in various areas of water conditioning in order to improve the quality of consumed water, as well as the need to develop methods for qualitative measurements of the optimal time parameters for the water residence in the denitrification filter when using it. The purpose of this research work is the practical development of methods for measuring the optimal time for the water residence in a denitrification filter, in order to find optimal opportunities for eliminating harmful and polluting substances from water used for domestic and industrial needs. The methodology of this research involves the use of a combination of methods for the systematic study of practical application issues of denitrification filters in water purification systems, using the method of qualitative analysis of water conditioning problems that are important with reference to the need to obtain high-quality water in volumes sufficient to meet the current domestic and industrial needs. The results of this research work are of great importance from the point of view of studying the problematic issues of determining the optimal time parameters for the water residence in modern filters, in order to achieve optimal indicators of the cleaning quality. The results and conclusions of this research are of considerable practical value for water filter designers, solving practical problems of creating high-quality denitrification filters, as well as for ordinary users, for whom the issues of water purification for its further practical application are of great importance

Nitrate filters are widely used in various sectors of the national economy for the purpose of stable degradation of nitrates without complex technological changes and control, as well as for obtaining, for practical use, water free from impurities of various polluting substances. The relevance of the stated research topic is determined by the wide use of filters in various areas of water conditioning in order to improve the quality of consumed water, as well as the need to develop methods for qualitative measurements of the optimal time parameters for the water residence in the denitrification filter when using it. The purpose of this research work is the practical development of methods for measuring the optimal time for the water residence in a denitrification filter, in order to find optimal opportunities for eliminating harmful and polluting substances from water used for domestic and industrial needs. The methodology of this research involves the use of a combination of methods for the systematic study of practical application issues of denitrification filters in water purification systems, using the method of qualitative analysis of water conditioning problems that are important with reference to the need to obtain high-quality water in volumes sufficient to meet the current domestic and industrial needs. The results of this research work are of great importance from the point of view of studying the problematic issues of determining the optimal time parameters for the water residence in modern filters, in order to achieve optimal indicators of the cleaning quality. The results and conclusions of this research are of considerable practical value for water filter designers, solving practical problems of creating high-quality denitrification filters, as well as for ordinary users, for whom the issues of water purification for its further practical application are of great importance

With the emergence of agriculture, humankind faced numerous difficult tasks. For example, how to use the potential of the soil while saving its quality and functional properties, how to apply agricultural technologies effectively and environmentally friendly, how to make them safe for human health and biota, and many others. There are several informative and reliable recording criteria and indicator systems that fully and comprehensively describe changes in the ecological condition of the soil and agrocenoses. However, all these systems have one defect – the time from the impact of the factor to the “reaction” of the indicator. Early diagnosis of changes in the agrocenosis is possible due to the biological component of the soil, namely the microbiocenosis. Notably, that microorganisms have a large contact surface with the environment, high rates of reproduction in space and time, sensitivity to changing living conditions. The reaction of soil microbiocenosis and its activity (number of microorganisms of ecological-trophic and taxonomic groups, respiration intensity, microbial biomass content, and soil phytotoxicity) under the action of chemicals that are the basis of plant protection products (PPP) was studied in the laboratory. It was found that the number of microorganisms of different ecological-trophic and taxonomic groups under the action of a composition of cymoxanil with dimetomorph decreased by 1.5-4.5 times relative to control, chlorperifos-methyl in 1.1-2 times, and prometryn – not more than 1.5. The content of microbial biomass and the intensity of carbon dioxide emissions when using cymoxanil with dimethomorph compared to the control variant decreased by 44% and 51.4-64.8%, respectively; prometryn – by 10-13% and by 8-12%. The highest level of soil phytotoxicity was observed for variants using prometryn (20-24%), the lowest for a composition of cymoxanil with dimetomorph (7-12%). It was shown, that the high level of inhibition of test culture development with the use of prometryn associated with the class of PPP and the mechanism of its effect on the plant organism. Low indicators of soil phytotoxicity and microbiocenosis activity when using cymoxanil with dimetomorph are explained by the influence of the studied composition not only on phytopathogenic micromycetes, but also on all groups of soil micromycetes (cellulose-destroying, saprophytic) that dominate. Therefore, the influence of PPP chemicals on the microbiocenosis can be shown as follows: PROMETRYN (the lowest level of influence) → CHLORPYRIFOS-METHYL → CYMOXANIL + DIMETOMORF (the highest level of influence)

With the emergence of agriculture, humankind faced numerous difficult tasks. For example, how to use the potential of the soil while saving its quality and functional properties, how to apply agricultural technologies effectively and environmentally friendly, how to make them safe for human health and biota, and many others. There are several informative and reliable recording criteria and indicator systems that fully and comprehensively describe changes in the ecological condition of the soil and agrocenoses. However, all these systems have one defect – the time from the impact of the factor to the “reaction” of the indicator. Early diagnosis of changes in the agrocenosis is possible due to the biological component of the soil, namely the microbiocenosis. Notably, that microorganisms have a large contact surface with the environment, high rates of reproduction in space and time, sensitivity to changing living conditions. The reaction of soil microbiocenosis and its activity (number of microorganisms of ecological-trophic and taxonomic groups, respiration intensity, microbial biomass content, and soil phytotoxicity) under the action of chemicals that are the basis of plant protection products (PPP) was studied in the laboratory. It was found that the number of microorganisms of different ecological-trophic and taxonomic groups under the action of a composition of cymoxanil with dimetomorph decreased by 1.5-4.5 times relative to control, chlorperifos-methyl in 1.1-2 times, and prometryn – not more than 1.5. The content of microbial biomass and the intensity of carbon dioxide emissions when using cymoxanil with dimethomorph compared to the control variant decreased by 44% and 51.4-64.8%, respectively; prometryn – by 10-13% and by 8-12%. The highest level of soil phytotoxicity was observed for variants using prometryn (20-24%), the lowest for a composition of cymoxanil with dimetomorph (7-12%). It was shown, that the high level of inhibition of test culture development with the use of prometryn associated with the class of PPP and the mechanism of its effect on the plant organism. Low indicators of soil phytotoxicity and microbiocenosis activity when using cymoxanil with dimetomorph are explained by the influence of the studied composition not only on phytopathogenic micromycetes, but also on all groups of soil micromycetes (cellulose-destroying, saprophytic) that dominate. Therefore, the influence of PPP chemicals on the microbiocenosis can be shown as follows: PROMETRYN (the lowest level of influence) → CHLORPYRIFOS-METHYL → CYMOXANIL + DIMETOMORF (the highest level of influence)

Allergic examination using PPD-tuberculins is the main method of life-time tuberculosis diagnostics in farm animals and poultry. However, it is known about a decrease in the diagnostic value of allergic reactions after irradiation of animals, the occurrence of non-specific, pseudo-allergic reactions. One of the reasons for the manifestation of non-specific reactions may be autosensitisation (autoallergisation) of the body by the breakdown products of personal tissues, which is especially pronounced with radiation damage. Ionizing radiation affects the manifestation of tuberculin sensitivity, the course of tuberculosis and autoimmune processes in the body. Differential diagnostics of non-specific tuberculin reactions remains not yet a fully solved problem, although there are many tests for its implementation. After the accident at the Chernobyl nuclear power plant, a considerable number of animals remained in the adjacent territories contaminated with radioactive substances, including those infected with the causative agent of tuberculosis and atypical mycobacteria. It is known that irradiation leads to autosensitisation of the body by the breakdown products of its own tissues and the development of non-specific pseudoallergic reactions to heterologous allergens. Therefore, work was carried out to study the allergic reactivity of tuberculosis patients and laboratory animals sensitised with atypical mycobacteria irradiated with gamma radiation (200 guinea pigs). It was established that 14-60 days after infection with tuberculosis pathogens, 90-100% of cavies developed allergic reactions to PPD-tuberculin for mammals and poultry, mainly to a homologous allergen. Allergic reactivity persisted until 90 days of the study. After exposure to sublethal (non-lethal) doses of gamma rays, infected and intact cavies developed non-specific reactions to tuberculin and heterologous allergens: mallein and brucellin. In cavies uninfected with the causative agent of tuberculosis, 7 days after gamma radiation exposure, non-specific reactions to mycobacterial allergens were observed at a dose load of 200 R in 16.6%; 150 R – 5.3% in the group, and after 27 days in irradiated doses of 50 R and 100 R in 25% and 33% of the studied animals, respectively. Isolated reactions to brucellin and mallein occurred in animals infected with the causative agent of tuberculosis and intact animals 60 days after irradiation with doses of 50 R, 100 R and 150 R. The manifestation of non-specific allergies in irradiated animals depended on the radiation dose rate and radiosensitivity of the animals

Allergic examination using PPD-tuberculins is the main method of life-time tuberculosis diagnostics in farm animals and poultry. However, it is known about a decrease in the diagnostic value of allergic reactions after irradiation of animals, the occurrence of non-specific, pseudo-allergic reactions. One of the reasons for the manifestation of non-specific reactions may be autosensitisation (autoallergisation) of the body by the breakdown products of personal tissues, which is especially pronounced with radiation damage. Ionizing radiation affects the manifestation of tuberculin sensitivity, the course of tuberculosis and autoimmune processes in the body. Differential diagnostics of non-specific tuberculin reactions remains not yet a fully solved problem, although there are many tests for its implementation. After the accident at the Chernobyl nuclear power plant, a considerable number of animals remained in the adjacent territories contaminated with radioactive substances, including those infected with the causative agent of tuberculosis and atypical mycobacteria. It is known that irradiation leads to autosensitisation of the body by the breakdown products of its own tissues and the development of non-specific pseudoallergic reactions to heterologous allergens. Therefore, work was carried out to study the allergic reactivity of tuberculosis patients and laboratory animals sensitised with atypical mycobacteria irradiated with gamma radiation (200 guinea pigs). It was established that 14-60 days after infection with tuberculosis pathogens, 90-100% of cavies developed allergic reactions to PPD-tuberculin for mammals and poultry, mainly to a homologous allergen. Allergic reactivity persisted until 90 days of the study. After exposure to sublethal (non-lethal) doses of gamma rays, infected and intact cavies developed non-specific reactions to tuberculin and heterologous allergens: mallein and brucellin. In cavies uninfected with the causative agent of tuberculosis, 7 days after gamma radiation exposure, non-specific reactions to mycobacterial allergens were observed at a dose load of 200 R in 16.6%; 150 R – 5.3% in the group, and after 27 days in irradiated doses of 50 R and 100 R in 25% and 33% of the studied animals, respectively. Isolated reactions to brucellin and mallein occurred in animals infected with the causative agent of tuberculosis and intact animals 60 days after irradiation with doses of 50 R, 100 R and 150 R. The manifestation of non-specific allergies in irradiated animals depended on the radiation dose rate and radiosensitivity of the animals

The energy efficiency of new technical developments is a critical issue. It should be noted that today the focus in this issue has seen a major shift to the maximum use of renewable energy sources. The purpose of this research is to reduce the weight of helium heat exchangers of the fuel tank pressurisation systems in modern rocket propulsion systems that use fuel components like liquid oxygen and kerosene-type fuel. This is the first time that the question has been raised about the possibility and advisability of increasing the temperature of helium at the heat exchanger inlet without the use of additional resources. The paper addresses the use of the waste (“low-potential”) heat and ”industrial wastes” present in propulsion systems. Basic laws of complex heat exchange and the retrospective review of applicable heat exchanger structures are applied as a research methodology. Two sources of low-potential heat are identified that have been previously used in the rocket engine building in an inconsistent and piecemeal manner to obtain and heat the pressurisation working fluid. These are the rammedair pressurisation during the motion of the rocket carrier in the atmosphere, and the tank pressurisation as a result of boiling of the top layer of oxidiser which is on the saturation line. This is the first time that the advisability has been substantiated of increasing the temperature of the working fluid at the heat exchanger inlet, first of all due to the use of the low-potential heat. This is also the first time that unemployed sources of low-potential heat and “industrial wastes” are found in modern deep throttling propulsion systems. These are the high-boiling-point fuel in the tank, behind the highpressure pump, at the exit of the combustion chamber cooling duct, and also the fuel tank structures, and the engine plume. A possibility is proved, and an advisability demonstrated of their implementation to increase the efficiency of pressurisation system heat exchangers. This is the first time that the methodology of combustion chamber cooling analysis has been proposed to be adopted for the heating of heat exchanger by the engine plume. This is the first time that a classification of waste heat sources has been developed which can be used to increase the pressurisation working fluid temperature. The identified reserves help to increase the efficiency of the helium heat exchangers of the tank pressurisation systems in the propulsion systems

The energy efficiency of new technical developments is a critical issue. It should be noted that today the focus in this issue has seen a major shift to the maximum use of renewable energy sources. The purpose of this research is to reduce the weight of helium heat exchangers of the fuel tank pressurisation systems in modern rocket propulsion systems that use fuel components like liquid oxygen and kerosene-type fuel. This is the first time that the question has been raised about the possibility and advisability of increasing the temperature of helium at the heat exchanger inlet without the use of additional resources. The paper addresses the use of the waste (“low-potential”) heat and ”industrial wastes” present in propulsion systems. Basic laws of complex heat exchange and the retrospective review of applicable heat exchanger structures are applied as a research methodology. Two sources of low-potential heat are identified that have been previously used in the rocket engine building in an inconsistent and piecemeal manner to obtain and heat the pressurisation working fluid. These are the rammedair pressurisation during the motion of the rocket carrier in the atmosphere, and the tank pressurisation as a result of boiling of the top layer of oxidiser which is on the saturation line. This is the first time that the advisability has been substantiated of increasing the temperature of the working fluid at the heat exchanger inlet, first of all due to the use of the low-potential heat. This is also the first time that unemployed sources of low-potential heat and “industrial wastes” are found in modern deep throttling propulsion systems. These are the high-boiling-point fuel in the tank, behind the highpressure pump, at the exit of the combustion chamber cooling duct, and also the fuel tank structures, and the engine plume. A possibility is proved, and an advisability demonstrated of their implementation to increase the efficiency of pressurisation system heat exchangers. This is the first time that the methodology of combustion chamber cooling analysis has been proposed to be adopted for the heating of heat exchanger by the engine plume. This is the first time that a classification of waste heat sources has been developed which can be used to increase the pressurisation working fluid temperature. The identified reserves help to increase the efficiency of the helium heat exchangers of the tank pressurisation systems in the propulsion systems