On the basis of the spent research high enough preventive efficiency of Ehrakond application, low intensive laser radiation together with a constant magnetic field is defined that allows to recommend them for wide application in the program of immunocorrection of an organism of agricultural animals. At the first stage of the research in immune deficiency when in blood of newborn calves almost there are no antibodies, influence on biologically active points of an udder of cows (intensity 10 mW/square cm, expositions of seconds) has made positive impact on increase of immune properties of colostric milk. Use of immunostimulants Ehrakond also has increased immunocompetent properties of cow milk (7,5 mg on 1 kg of body weight once a day within 15 days). At feeding of colostrum the physiological condition, growth and development of calves have considerably improved. In the second (when colostric protection factors in an organism decline, and own organism forms them insufficiently) and the third (decrease in immune reactance at changes in feeding and the maintenance of calves) immune deficiency, application of immunostimulants Ehrakond and influence of low intensive laser radiation together with a constant magnetic field on reflexogenic zones on a young growth organism has made positive impact indices of natural resistance of calves. It has led to activization of factors of natural nonspecific protection of an organism that has considerably improved a physiological condition and has increased natural immunity of an organism to diseases. However, the best results on natural resistance, efficiency and safeties of calves have been reached at an irradiation at the BAP initial stage of a mammary gland at cows by low intensive laser radiation together with a constant magnetic field, with the subsequent bottle-feeding of the irradiated colostrum to newborn calves; in 10 days of a life to calves the preparation Ehrakond was entered. | На основании проведенных исследований определена достаточно высокая профилактическая эффективность применения Эраконда, низкоинтенсивного лазерного излучения совместно с постоянным магнитным полем, что позволяет рекомендовать их для широкого применения в программе иммунокоррекции организма сельскохозяйственных животных. На первом этапе исследований в период иммунного дефицита, когда в крови новорожденных телят почти отсутствуют иммуноглобулины, воздействие на биологически активные точки вымени коров (интенсивность 10 мВт/см2, экспозиции секунд) оказало положительное влияние на повышение иммунных свойств колострального молока. Использование иммуностимулятора Эраконд также повысило иммунокомпетентные свойства молока коров (7,5 мг на 1 кг живой массы один раз в сутки в течение 15 дней). При скармливании колострального молозива значительно улучшились физиологическое состояние, рост и развитие телят. В период второго (когда колостральные факторы защиты в организме угасают, а собственный организм образует их недостаточно) и третьего (снижение иммунной реактивности при изменениях в кормлении, содержании телят) иммунного дефицита, применение иммуностимулятора Эраконд и воздействие низкоинтенсивного лазерного излучения совместно с постоянным магнитным полем на рефлексогенные зоны на теле молодняка оказало положительное влияние показатели естественной резистентности телят. Это привело к активизации факторов естественной неспецифической защиты организма, что значительно улучшило физиологическое состояние и повысило естественную невосприимчивость организма к болезням. Однако, наилучшие результаты по естественной резистентности, продуктивности и, сохранности телят были достигнуты при облучении на начальном этапе БАТ молочной железы у коров низкоинтенсивным лазерным излучением совместно с постоянным магнитным полем, с последующим выпаиванием облученного молозива новорожденным телятам; через 10 дней жизни телятам вводили препарат Эраконд.

Studying of palatability of bait blisters applied for oral immunization of wild carnivores against rabies was realized in the conditions of the Republic of Belarus by an example of foxes which were administrated with liquid viral vaccines against rabies. Foxes were divided into 5 groups with 8 animals in each. Animals of the first group were immunized with a liquid viral vaccine in blister baits Lisvulpen-VBF which was produced from an attenuate strain of rabies virus SAD-BERN (Belarus). Animals of the second group were immunized with liquid viral vaccine Belvak TM BP produced from the cultural living strain KMIEhV-V101 (Belarus). Animals of the rest three groups were immunized with liquid viral vaccine in blister baits which was produced from a modified strain of a fixed attenuate rabies virus KMIEV-94. Foxes of the forth group were additionally fed with ascorbic acid with baits in the doze of 0,1 g, and foxes of the fifth group were fed with 5 ml immune response modifier Nuklevit. All mentioned blister baits were studied in accordance with the following parameters: bait flavor and attraction to animals; form and size of bait; bait consistency; blister and its size in relation to bait; palatability of bait; degree of damage of bait containing a vaccine; quantity vaccine which was got into animal oral cavity; postvaccinal complication. Palatability of liquid viral vaccines in blister baits Lisvulpen-VBF was 96%, Belvak TM BP - 94%, KMIEV-94 - 80%

Feeding replacement heifers of 6-12 months of age with mixed feed that contains 20-25% of rape and lupine grain within winter and summer diets instead of sunflower cake allows to obtain the average daily weight gain of 893-927 g at forage spends of 6,0-6,3 с of forage units. The cost of these mixed feeds is decreased at 14% and prime cost of 1 c of weigh gain-at 6-15%

Data on studying of efficiency of application of immunobiological preparations on efficiency and other clinical and biochemical indicators for chickens-broilers are cited. It is established, that their application to chickens-broilers promotes increase of biological value of fowl as foodstuff and is economically expedient. Application of a preparation the Biococktail-NK in an optimum dose 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) has allowed to increase intensity of growth of chickens-broilers by 3,5%, to lower forage expenses for production of a gain of body weight of 1 kg on 4,95%, to raise safety of young growth of birds on 3,4 % and to lower a case of birds to 1,6% (technological norm of 5%). The carried out calculations have shown, that introduction of the Biococktail-NK in a ration of broilers is economically justified, as safety of young growth in 4th trial group has raised on 3,4%, in the third - on 2,5%, in the second - on 1,3%. On the basis of the spent research fowl of the delivered samples in which ration it was entered the probiotic Biococktail-NK from calculation 0,1 - 0,2 ml/goal (10,0-20,0 million microbic bodies) since daily age within the first 5 days into 4 cycles with an interval of 7 days till the end of the cultivation period is established, that on organoleptic, physical and chemical, bacteriological indicators, and also biological value and harmlessness does not concede to meat of control group and is good-quality. In the literature there are data about influence of biologically active substances on growth and development of bird. Despite it, about influence of probiotical and immunostimulatory preparations as separately, and in a complex with probiotics, on an organism of chickens-broilers it is not enough data that induces carrying out of scientific research in the given direction. Simultaneous use of probiotics on the basis of an intestinal stick in rations of chickens-broilers is the perspective directions. Proceeding from it, working out of new effective ways of increase of chickens-broilers efficiency with a view of reception of ecologically pure and safe products of poultry farming is actual for poultry-farming economy of Belarus.

Balanced complete feeding proved to be one of the major conditions of animal productivity increase and improvement of their reproductive qualities. Full value of feeding could be obtained at the expense of forage quality improvement and perfection of structure of the rations providing the increasing of metabolic energy use by breeding bull-calves. Analysis of the efficiency of metabolic energy use by the replacement bull calves under conditions of various sugar and protein ratio was realized in the Republic of Belarus. Research results showed that enrichment of replacement bull calves (with 325-405 kg of live weight) rations with easy digestible carbohydrates (sugar and starch) in ratio of 32% from a dry matter ration, including 15% of stable starch made it possible to increase the transformation of metabolic energy into energy of body weight gain on 21,73 - 23,96 MJ or on 10,3%, that as a result correspondingly increased the daily average weight gains on 7,9% and reduced the expenses for forage energy for 7,1% counting on an energy unit. According to the ejaculate volume indices the bull calves of the second experimental group surpassed analogues of a control group on 14,8%, and according to sperm concentration indices - on 12%. The average quantity of the frozen doses of sperm has made 65%

There was developed a method of increasing the efficiency of used feeds and poultry productivity by means of stimulations of natural resistance of an organism by biologically active substances (Vigozin preparation, containing carnitine). Application of preparation Vigozin with potable water twice in a dose of 1 ml on 1 l of water within first 3 days and for 13th day of cultivation allows to raise safety of chickens-broilers on 2,3% at the expense of normalization of metabolism at young growth and preservation of a functional condition of a liver. Results of the general clinical and the immunological analysis of blood at chickens-broilers of control and trial groups (M+/-m, n=10), biochemical indicators of blood at chickens-broilers of control and trial groups in age dynamics (M+/-m, n=10) are presented. | Целью работы являлось научное обоснование и разработка способа повышения эффективности использования кормов и продуктивности птицы путем стимуляции естественной резистентности организма биологически активными веществами (препарат Вигозин, содержащий карнитин). Применение препарата Вигозин с питьевой водой двукратно в дозе 1 мл на 1 л воды в течение первых 3-х суток и на 13-й день выращивания позволяет повысить сохранность цыплят-бройлеров на 2,3% за счет нормализации обмена веществ у молодняка и сохранения функционального состояния печени. Представлены результаты общего клинического и иммунологического анализа крови у цыплят-бройлеров контрольной и опытной групп (M+/-m, n=10), биохимические показатели крови у цыплят-бройлеров контрольной и опытной групп в возрастной динамике (M +/- m, n=10).

In the conditions of the Republic of Belarus there was analyzed the efficiency of application of an adsorbent mycotoxins Toxfin Dry (Belgium) for lowering of toxicity load on broiler chickens. In the course of the study there was given attention to poultry productivity, viability and forage expenses for broiler chickens breeding. There was developed a scheme of Toxfin Dry preparation feeding to broiler chickens. There were presented the results of weighing of control and experimental broiler chickens during the breeding periods; the basic zootechnical indices in the conditions of introduction Toxfin Dry; economic efficiency of its application. Research results showed that introduction of a mycotoxin adsorbent Toxfin Dry into diets of broiler chickens promoted the improvement of digestion and absorption of mixed fodder nutrients in a gastroenteric tract, that in its turn promoted the increasing daily average weight gain on 4,3%, broiler stock viability - on 2,6%; and to decrease the expenses for forages on 13,9%. On the basis of obtained experimental data it was recommended to include the mycotoxin adsorbent Toxfin Dry into rations of broiler chickens as a dry mix with mixed fodder in a dose of 5 g/kg of forage dry matter.