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Ethological Problems and Learning Disability due to Aluminium Toxicity in Rats
2013
Amira, A. Goma | U. E. Mahrous
A total of 35 Sprague-Dawley adult rats were used to investigate the effect of aluminium toxicity on behavioural patterns of adult female rats and learning ability of offspring. Rats were allotted into 4 groups, group one received 2g/l anhydrous aluminium chloride (n=10), group two received 3g/l anhydrous aluminium chloride (n=10), group three received 3.5g/l anhydrous aluminium chloride in drinking water (n=10) and control group did not receive anhydrous aluminium chloride (n=5) from 8th day of pregnancy till weaning of pups. The obtained results showed that feeding time increased significantly in 2g/l and 3.5g/l anhydrous aluminium chloride groups than control one, while, litter licking frequency and nursing time increased significantly in 2g/l anhydrous aluminium chloride than other groups. On contrary lying time decreased significantly in rats treated with 2g/l anhydrous aluminium chloride than other groups, licking and scratching decreased in 3g/l and 3.5g/l anhydrous aluminium chloride groups. In considering, the time spent in closed arms by offspring pups exhibited much times significantly than control group, while, time spent in open arms of elevated plus maze decreased significantly in all treated groups than control group. On the other hand, number of entries in open arms significantly decreased in treated groups than control one.
اظهر المزيد [+] اقل [-]A case report of diagnosis and treatment of metastatic calcinosis circumscripta secondary to chronic renal failure
2005
Park, S.J. (Chungnam National University, Daejeon, Republic of Korea) | Park, H.Y. (Chungnam National University, Daejeon, Republic of Korea) | Jeon, S.B. (Chungnam National University, Daejeon, Republic of Korea) | Choi, H.J. (Chungnam National University, Daejeon, Republic of Korea) | Jeong, S.M. (Chungnam National University, Daejeon, Republic of Korea) | Song, K.H. (Chungnam National University, Daejeon, Republic of Korea) | Cho, J.K. (Chungnam National University, Daejeon, Republic of Korea) | Lee, Y.W. (Chungnam National University, Daejeon, Republic of Korea) | Shin, S.T. (Chungnam National University, Daejeon, Republic of Korea) | Kim, M.C. (Chungnam National University, Daejeon, Republic of Korea) | Kim, D.H. (Chungnam National University, Daejeon, Republic of Korea), E-mail: dhkim@cnu.ac.kr
A 1.35 kg, three-year-old, female, Yorkshire terrier was referred to the veterinary medical teaching hospital of Chungnam National University with an alopecia, scale, polydipsia and polyuria. During hospitalization, the patient revealed swelling and pain of all four foot pads. The hematology indicated nonregenerative anemia. Blood serum chemistry revealed elevation of BUN, serum creatinine and phosphorus contents. Radiographs of feet revealed increased radiodensity in the soft tissue of the foot pad. In ultrasonographs of abdomen, kidneys showed diffusely echodense renal cortex with loss of the normal corticomedullary boundary.
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