In the conditions of the Republic of Belarus there was studied the influence of electroactive solutions of anolyte neutral, catholyte alkaline and hypochlorite sodium on microbial flora of a gastro enteric path of calves and sheep. In course the realized research it was stated that more expressed action of anolyte neutral and hypochlorite sodium on beneficial microflora of animal intestines (namely, the decrease in quantity of some indexes) can probably be explained by an expressed antimicrobic action of the analyzed solutions. However, the quantitative changes occurring in composition of microbial flora were not so great and cannot cause radical changes of a microbial landscape of gastro-intestinal tract. Less expressed influence on microbial flora of intestines of calves and sheep rendered the solution of alkaline catholyte. Taking into consideration the expressed regenerative properties of the studied electroactive solution, it was possible to assume, that according to the mode of action of the preparation, its application will promote the increasing of protective forces of an organism without causing any radical changes of a microbial landscape of intestines of animals. The problem of influence of electroactive solutions on a microbial landscape of a gastro enteric tract of animals demands the further studying, however at the given stage it is possible to make a conclusion, that the quantitative changes of the microbial flora which were caused by application of the analyzed solutions, proved to be less fatal and did not render sharp negative influence on a microbial landscape as a whole. Taking into consideration data of the realized research it is possible to make a conclusion on possibility of application of the electro activated solutions of anolyte neutral, catholyte alkaline and hypochlorite sodium for treatment of gastro enteric tract diseases of agricultural animals.

Study of sensitivity of Paenibacillus alvei to different antibiotic preparations (penicillin, tetracycline, neomycine, kanamycin, ampicillin, polymyxin, laevomycetin, enrofloxacin, tylosin, and streptomycin) was realized in the conditions of the Republic of Belarus. As the material of the research there was used the culture of agent the European foul brood caused by Paenibacillus alvei. Determination of therapeutic effectiveness of antibacterial agents in vitro conditions made it possible to choose the appropriate preparation for its use at beeyards with European foul brood caused by Paenibacillus alvei. During the experimental work there were used 10 antibacterial disks with various antibiotics. The best result against Paenibacillus alvei was shown by Tilozin, the diameter zone of growth inhibition was about 47,2+/-3,43 mm.

Sensitivity of European Faulbrut causative agent to Gentavet preparation was studied in the conditions liquid nutritive media in vitro in the Republic of Belarus. Research results showed that the studied preparation rendered the poisonous influence on European Faulbrut causative agent in concentration of 0,3 mkg/ml with the maximum rate 1:131072. The antibiotic showed the bacteriostatic ability in concentration of 0,15 mkg/ml. The antibacterial preparation did not influence the European Faulbrut causative agent in concentration of 0,01 mkg/ml. The total bacteriostatic effect the drug showed in concentration of 0,22 mkg/ml and its dilution of 1:196608.

For the well-timed prevention and treatment of sick animals there was analyzed the therapeutic efficiency of a produced survivor serum against acute respiratory diseases of sheep and lambs, as well as Catosal in combination with Nitox 200 against the mixed flow of parainfluenza-3, adenovirus, respiratory syncytial, chiamydial and pasteurellosis infection. Comparative efficiency of all mentioned preparations was presented. Research results showed the correct and timely application of drug preparations as well as their qualitative selection made it possible to lower the death cases. Application of the presented survivor serum in combination with Nitox 200 and Catosal made it possible to lower the loss of cattle in 4-5 times and increase the viability rate of animals