BACKGROUND: Babesiosis and Thosis are parasitic tick-borne diseases that cause a lot of economic loss in livestock Industry. Objectives: The purpose of the present study was to detect Babesia and Theileria infection in goats and and vector ticks in goats in Mashhad. Methods: One hundred blood samples of goats and 246 ticks were collected from some suspected flocks with history of piroplasmosis. The samples were transported to laboratory under cold condition. Blood smears were prepared and stained by Geimsa method and examined with a light microscope at ×1000 magnitude. The collected ticks were separated into tick pools of five according to their species and sex. The blood, salivary gland and ovaries of tick samples were examined using specific primers of Babesia.spp and Theileria.spp by semi nested-PCR. Results: Piroplasm bodies were not observed in any blood samples of goat in Mashhad. In a total of 246 collected ticks, seven species were identified as follows: R. turanicus 127(51.6%), D. marginatus 67 (27.2%), Hy. marginatum 44 (17.9%), R. sangunincus 4(1.6%), Hy. anatolicum 2(0.8%), Hy. asiaticum 1(0.4%) and Heam. sulcata 1(0.4%). Dominant tick species of goats in Mashhad suburb were R. turanicus and D. marginatus. The results of PCR showed that none of the blood samples were infected with Babesia spp. and Theileria spp. Also, Theileria infectoin was detected in a sample salivary glands  of Hy. marginatum. ConclusionS: Based on microscopic and molecular results, no  Theileria spp. and Babesia spp. infection were detected in goats. R.turanicus was the dominat tick species and Theileria spp. infection was detected in one sample of Hy.marginatum.

Ticks are blood-sucking arthropods that have negative economic impacts and can spread a variety of diseases through their bites. There are few reports on soft ticks (Acari: Argasidae) and tick-borne pathogens in southern Xinjiang, China. This investigation supplements the available information for this region and is concerned with an argasid tick, apicomplexan parasites of the Babesia and Theileria genera and a bacterium of the Anaplasma genus.

We evaluated the efficacy of buparvaquone in eliminating infection with Babesia equi of European origin in carrier horses and in splenectomized horses with experimentally induced acute infection. When administered at the rate of 5 mg/kg of body weight, IV, 4 times at 48-hour intervals, buparvaquone prompted rapid abatement of parasitemia. However, secondary and tertiary recrudescent parasitemias invariably returned with establishment of the carrier state. Buparvaquone, at the dosage evaluated, had transitory therapeutic efficacy against acute B equi infection in splenectomized horses, but was unable alone to clear carrier infection.

Babesia bovis, cattle, kinetics of specific indirect fluorescent antibody test titers and total serum IgG and IgM values after vaccination and challenge exposure, nonspecific suppression of total IgG and IgM values coinciding with period of peak parasitemia

Babesia bovis, nonviable tissue culture-derived antigens as vaccine in cattle, comparison with premunition

Babesia bigemina infection in population of Boophilus decoloratus cannot be eliminated in short term by treating cattle prophylactically with imidocarb dipropionate, Babesia retained by ticks for at least complete generation

A comprehensive study was conducted on the clinical observationsincluding clinical history, physical examination along with haematobiochemical alteration on 41 naturally occurring cases of canine babesiosis from Punjab state, India. Examination of 964 dogs revealed 4.25 percent (41/964) prevalence of the disease including 3.84 percent (37) B. gibsoni and 0.41 percent (4) B. canis infected cases. Clinical and parasitological diagnosis was finally confirmed by polymerase chain reaction. A large variation of clinical anifestations including rare findings of paraplegia, blindness, ocular bleeding, immune mediated haemolytic anaemia (IMHA), ascites and skin lesions were observed among the affected animals. Bloodfilms showed anisocytosis and nucleated erythrocytes indicating regenerative anaemia. Blood parameters of the affected dogs revealed significant decrease in Hb, TEC, PCV and thrombocytes. Significantdecrease in lymphocytes was found in B. gibsoni affected animals. The affected dogs showed significant increase in serum bilirubin, ALT, AKP, BUN and creatinine. Haemato-biochemical observations wereindicative of severity of babesiosis in dogs.