خيارات البحث
النتائج 1 - 5 من 5
Study on natural killer cell activity and its characteristics during hepatocarcinogenesis in rats
1999
Jeong, J.Y. | Lee, K.K. | Kil, S.K. (Korea Food & Drug Administration, Seoul (Korea Republic). Department of Pathology, National Institute of Toxicological Research) | Lee, Y.S. (Seoul National University, Suwon (Korea Republic). College of Veterinary Medicine)
The purposes of this study were to set up the method of the natural killer(NK) cell activity assay using the flow cytometer and to examine the characteristics and distribution of the NK cell during rat hepatocarcinogenesis. Forty five male 6 week-old specific pathogen free(SPF) Sprague-Dawley rats were randomly divided into three groups. Group I was the non-treated control and given normal diet and water. Group II was treated with diethylnitrosamine(DEN, 200mg/kg, i.p.) and partial hepatectomy. Group III was treated with DEN, partial hepatectomy and 0.05% phenobarbital sodium in water from 3 to 16 weeks. All animals were examined the morphology of the large granular lymphocyte(LGL), the LGL percent of the total lymphocytes and the LGL conjugation rate with YAC-1 cell in peripheral blood, spleen and liver. Moreover, activity of the LGL isolated from peripheral blood lymphocytes was determined using the flow cytometer. As results, LGL were observed in the peripheral blood, spleen and liver. LGL were observed the relatively faintly staining basophilic cytoplasm with granules, and eccentric, often kidney-shpaed nuclei in Giemsa stain. Its size was 11~13 micro meter. LGL percentage of the isolated lymphocytes in peripheral blood, spleen and liver were 1.8~2.3%, 1.3~1.4% and 0.87~0.99%, respectively. LGL conjugation rate with YAC-1 cell was shown to be peripheral blood(9.3~10.3%) spleen(7.7%~8.7%)liver(5.6~7.0%). The activity of the LGL isolated from peripheral blood lymphocytes in Group I, II and III was 33.7%, 30.5% and 35.4%, respectively. However, all values were not sighificantly between groups.
اظهر المزيد [+] اقل [-]An immunohistochemical study on the gastro-entero-endocrine cells of the pond tortoise (Amyda sinensis)
1990
Kim, J.B. | Lee, J.H. | Lee, N.S. (Kyungpook National University, Taegu (Korea Republic). College of Veterinary Medicine) | Lee, H.S. (Taegu Oriental Medical College, Taegu (Korea Republic). Department of Biology)
Studies on properties and pathogenicity of Erysipelothrix rhusiopathiae isolated from pigs in Korea
1991
Yeh, J.G. (Bayer Veterinary Medical Research Inst., Anyang (Korea Republic)) | Seok, H.B. (Dankook Univ., Cheonan (Korea Republic). Coll. of Agriculture)
An immunohistochemical study of the endocrine cells in gastrointestinal tract of the Korean native goat
1990
Lee, J.H. (Kyungpook National University, Taegu (Korea Republic). College of Veterinary Medicine) | Lee, H.S. (Taegu Oriental Medical College, Taegu (Korea Republic). Department of Biology)
An immunohistochemical observation on the somatostatin cells in the gastrointestinal tract of the yonsan ogol fowl
1990
Ryu, S.Y. | Cho, S.W. (Chungnam National University, Taejon (Korea Republic). Department of Veterinary Medicine) | Lee, C.S. (Kyungpook National University, Taegu (Korea Republic). College of Veterinary Medicine) | Yamada, J. (Obihiro University of Agriculture and Veterinary Medicine, Obihiro (Japan). Department of Veterinary Medicine)
