Determination of possible relations between some metabolic activity indexes of Large White pregnant sows (with various pregnancy stages) and their offspring was realized in the conditions of the Republic of Belarus. In the experimental animals there was taken blood for hematologic and biochemical tests. In peripheral blood there was analyzed the average content of hemoglobin, total number of erythrocytes, leukocytes, thrombocytes and corpuscular volume. Content of total protein, albuminolesterin, concentration total kalium and nonorganic phosphorus, magnesium, iron, zinc, activity of alanine- and aspartate transaminase were evaluated in blood serum. Blood tests were made on 84th day of pregnancy, in 30 days before farrowing, on the 2-nd lactation day and on the 2-nd and 35-th days of piglet life. Research results showed high degree of persistence of iron and zinc deficiency of pregnant sows in the conditions of modern national swine production. The obtained results proved the presence of close relationship between metabolic processes of sows and piglets that was revealed in low degree of stores supply with elements which had been in deficit for their mothers

Studying of therapeutic effectiveness of metabolic probiotic Diamixan (sterile concentrate of waste products of Lactobacillus acidophilus, Lactobacillus debrueckii, and Streptococcus salivarius) against piglet gastroenteritis appearing at weaning period was realized in the conditions of the Republic of Belarus. The analyzed preparation contained complex of substances: bioartificial lactic acid, amino acids, polysaccharides, and some other ingdredients. In course of analysis of the state of intestinal microbiocenosis there were analyzed the following indexes: bifidus bacteria; lactic acid bacillus; E. coli; enterococcus; Proteus; Staphylococcus saprophyticus; Clostridia; yeast-like fungi; enterobacteria. Research results showed that application of the examined preparation made it possible to shorter the terms of animal recovery on 2,2 days, as well as to facilitate the severity of a disease. Bottle feeding of the metabolic probiotic promoted the stabilization and normalization of the main hematological indexes. The analyzed preparation created the optimal pH in lumen of the intestine, inhibited the rowth of opportunistic pathogenic bacteria, promoted quicker reconstruction of microecological status by means of normalization of standard flora of bifidus bacteria and lactic acid bacillus

Determination of a degree and stages of metabolic disorders of aborted sows and sows which gave birth to dead fetus was realized in the conditions of the Republic of Belarus. Analysis of biochemical profile of blood of experimental sows was given. Typical deviations of biochemical status indexes in the conditions of reproduction pathology were determined. The highest degree of deviations of biochemical blood profile (indexes of fat, protein and mineral metabolism) was stated at aborted sows. At sows which gave birth to dead fetus there were stated abnormalties functional state of kidneys and liver, indexes of carbohydrate and mineral metabolism.

Analysis of national studies and literary sources on problems of haemophilus pleuropneumoniae of swine was realized in the conditions of the republic of Belarus. Research was realized in the conditions of Agricultural Production Co-operative Uritskoe (Gomel region, Belarus). It was established that medical actions gave positive result only at early stages of disease.

Searching for new, effective and safe methods of treatment of hookworm disease (ancylostomatidosis) of dogs caused by Ancylostoma caninum and Uncinaria stenocephala was realized in the conditions of the Republic of Belarus on the basis of studying of spices composition and dissemination of Ankilostomatidae, age-specific and seasonal disease dynamics, testing of medical and preventive preparations Univerm and Fenbendazol. In the Republic of Belarus Ancylostoma caninum was stated 4,2% of studied cases and Uncinaria stenocephala – in 14,3%. The maximum intensity of the invasion was stated in summer and autumn periods: in cases of individual keeping – 19,4%; in cases of group keeping the disease transformed into enzootic form with 66,7% affect. In winter period there was the lowest invasion – up to 1,4%. The preparation Univerm administrated twofold with feed in dose of 0,1 mg/kg with 24 hours interval proved to be highly effective therapeutic agent with extensefficiency100%. Anthelmintic Fenbendazol administrated once with feed in dose of 0,005 g/kg proved to be highly effective with extensefficiency 80% and intensefficiency 98,84%. Hematological indexes of sick dogs showed the evidence of erythropenia (4,30-4,80 x 10E12/l), hemoglobinemia (113-119 g/l) and eosinophilia (up to 11%), as well as the increased quantity of leukocytes on 5,46% - 23,61 %, and the lowered quantity of lymphocytes on 15,84 % in comparison with healthy animals indexes

Realized in the conditions of the Republic of Belarus experimental infestation of American mink with monoinvasion of Strongyloides martis and parasitocoenoses of Strongyloides martis and Eimeria vison caused significant changes of hematological blood indices. Associations of the nematodes and coccids caused more intensive changes of blood morphological composition in comparison with monoinfection. The level of hemoglobin and erythrocytes at monoinvasion decreased on 18,8 % (р less than 0.05) and 23,3 % (р less than 0.05); in the conditions of an associative form - on 19,1 % (р less than 0.05)) and 31,4%, respectively; at the same time the quantity of leukocytes increased at monoinvasion on 41,3 % (р less than 0.05)), at the associative form - on 54,2 % (р less than 0.05)). In leucogram there were stated an eosonophilia and netrofilia.