خيارات البحث
النتائج 1 - 10 من 10
Neuromuscular and vascular hamartoma of the cecum in a dog النص الكامل
2019
Yamashita, M. (Tottori University, Tottori (Japan). Faculty of Agriculture, Joint Department of Veterinary Medicine) | Sunden, Y. | Osaki, T. | Tsuka, T. | Morita, T.
An unusual case of thoracic ectopia cordis in a toggenburg goat and its three-dimensional images constructed with X-ray computed tomography النص الكامل
2016
Lai, J.M. ((National Chiayi University, Chiayi City (Taiwan). Department of Veterinary Medicine), (National Chiayi University, Chiayi City (Taiwan). Veterinary Medicine Hospital)) | Wu, J.T. | Yang, W.C. | Chao, M.H. | Nagahata, H.
An intrathoracic ectopic liver with pleural effusion in a dog النص الكامل
2017
Iwaki, Y. (Hokkaido University, Sapporo, Hokkaido (Japan). Graduate School of Veterinary Medicine, Department of Veterinary Clinical Sciences, Veterinary Teaching Hospital) | Takagi, S. | Morishita, K. | Hanazono, K. | Hosoya, K. | Okumura, M.
Complex malformations of the urogenital tract in a female dog: Gartner duct cyst, ipsilateral renal agenesis, and ipsilateral hydrometra النص الكامل
2016
Fujita, A. (the University of Tokyo, Bunkyo-ku, Tokyo (Japan). Veterinary Medical Center) | Tsuboi, M. | Uchida, K. | Nishimura, R.
Sublethal concentrations of di-n-butyl phthalate promote biochemical changes and DNA damage in juvenile Nile tilapia (Oreochromis niloticus) النص الكامل
2016
Khalil, S.R. (Zagazig University (Egypt). Faculty of Veterinary Medicine, Forensic Medicine and Toxicology Department) | Elhakim, Y.A. | El-Murr, A.E.
Evaluation of immunohistochemical staining with PMab-38, an anti-dog podoplanin monoclonal antibody, in various canine tumor tissue النص الكامل
2019
Kiname, K. (The University of Tokyo, Bunkyo-ku, Tokyo (Japan). Graduate School of Agricultural and Life Sciences, Laboratory of Veterinary Surgery) | Yoshimoto, S. | Kato, D. | Tsuboi, M. | Tanaka, Y. | Yoshitake, R. | Eto, S. | Shinada, M. | Chambers, J. | Saeki, K. | Kinoshita, R. | Yamada, S. | Uchida, K. | Kaneko, M.K. | Nishimura, R. | Kato, Y. | Nakagawa, T.
Complete atrioventricular block due to primary cardiac lymphoma in a dog النص الكامل
2018
Sasaki, T. (Tokyo University of Agriculture and Technology, Fuchu, Tokyo (Japan). Laboratory of Veterinary Clinical Oncology) | Kimura, Y. | Imai, T. | Machida, N.
Pericardial mesothelioma with severe congestive heart failure in a Holstein cow النص الكامل
2017
Suzuki, H. (Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido (Japan). Department of Veterinary Medicine) | Watanabe, K. | Horiuchi, N. | Kobayashi, Y. | Inokuma, H.
Lambda cyhalothrin toxicity induces alterations in lipogenic genes and inflammatory factors in rat liver النص الكامل
2016
Moustafa, G.G. (Zagazig University (Egypt). Faculty of Veterinary Medicine, Department of Forensic medicine and Toxicology) | Hussein, M.M.A.
Upregulation of renal renin-angiotensin system in mouse diabetic nephropathy
2005
Tamura, J.(Hokkaido Univ., Sapporo (Japan)) | Konno, A. | Hashimoto, Y. | Kon, Y.
The aim of this study was to clarify the role of the renal renin-angiotensin system (RAS) in diabetic nephropathy (DN) , which was induced by injection of streptozotocin (STZ). Male CBA/N and CBA/J mice were compared in this study. The former possesses a single renin gene, Ren1. whereas the latter carries two renin genes, Ren1 and Ren2. To examine the molecular dynamics of renal RAS, including renin, angiotensinogen (Agt), angiotensin-converting enzyme (Ace), angiotensin type 1 (Agtr1) and type 2 (Agtr2) receptors in experimental DN, we performed laser-microdissection (LMD) followed by reverse transcriptase nested polymerase chain reaction using each specific primer pairs and immunohistochemistry for renin and angiotensin 2. CBA/N mice had a higher response after injection of STZ than CBA/J mice, showing a significant increase of the kidney/body weight ratio, although there was no significant difference between the two strains for the blood glucose level or pancreatic beta-cell response. The onset of renal pathological changes associated with DN was earlier and more severe in CBA/N mice than in CBA/J mice. Distinct immunoreactivities for renin and angiotensin 2 were newly distributed on the flattered epithelial cells in the dilated distal tubules in the cortex as well as the collecting ducts in the cortex and medulla, and were demonstrated more intensity in CBA/N mice than in CBA/J mice. Micro dissectional analysis in both models revealed a higher incidence of RAS-related gene expression in CBA/J, Ren 2 mice than in CBA-N, Ren 1 mice.
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