Objective—To determine the mode of inheritance for cerebellar abiotrophy (CA), a neurologic disease in Arabians. Animals—804 Arabians, including 29 horses (15 males and 14 females) with CA. Procedures—Most horses (n = 755) belonged to 1 of 4 paternal families. Among the 29 CA-affected horses, all had clinical signs consistent with the disease; the disease was confirmed histologically following euthanasia in 8 horses. From the pedigree information, inbreeding coefficients were calculated for 16 affected horses and compared with coefficients for a subgroup of 16 unaffected horses. Complex segregation analysis was used to determine the effect of a putative Mendelian locus on the development of the disease and the probable mode of inheritance of CA. Results—The mean inbreeding coefficient was 0.0871 for CA-affected and unaffected horses, suggesting that all of the Arabians were inbred to the same degree and that affected horses were not more inbred than were unaffected horses. Results of the complex segregation analysis were consistent with a single Mendelian autosomal recessive mode of inheritance. Conclusions and Clinical Relevance—Knowledge of the mode of inheritance of CA should help breeders to make informed decisions regarding the selection of animals for mating when closely related horses have developed CA or produced CA-affected foals.

Data relating to 130 sows, 19 boars from 400 farrrowings spread over a period from 1984 to 1992 were utilized to study genetic and non-genetic effects in variation of litter size and weight at birth and at weaning. The overall mean litter size at birth (LSB)was 6.83 ± 0.13 piglets. The effects of period, season of farrowings and inbreeding on litter size at birth were not significant (P>0.05).The overall least squares mean of litter size at weaning(LWW) was 4.83 ± 0.12 and was significantly (Pd”0.05) affected by in breeding. Litter weight at birth (LWB) had a least square mean of 7.81 ± .16 kg and it was significantly (Pd”0.05) affected by period of farrowing. The mean LWB of non-inbred sows was 8.22 ± 0.19kg and that of inbred sows was7.41 ± 0.29 kg. The overall least squares mean for litter weight at weaning (LWW) was 39.36 ± 1.25 kg and inbreeding of sow exerted significant effect on LWW. The LWB and LWW were significantly affected by period of farrowing. The litter size at birth and at weaning and litter weight at birth and at weaning was not significantly affected by season of birth. The heritability estimates of litter size at birth and litter size at weaning were 0.096 ± 0.09 and 0.816 ± 0.27 respectively. The corresponding heritability values for LWB and LWW were 0.41 ± 0.18 and 0.53 ± 0.21 respectively. 

A survey was conducted to assess the breeder production performance in Aseel breeding farms. Aseel birds had multicolored plumage with solid feather patterns distributed all over the body. Pea combs, strawberry and single comb were observed in the population. Birds were housed in layer shed with the ratio 1 male for 8 female. Age at first egg was  recorded as 139±1.94 days. Average cumulative egg production up to 120 weeks per bird was 160.59±0.59 with the 77% hatchability. Percentage hen day egg production for Aseel was 29.72±1.60 and the effective population size (Ne) ranged from 352.94 to 4781.16 and the overall mean Ne in the Aseel population was 2086.59±148.35 with the rate of inbreeding 0.0003.

To conduct ex-situ creole pig conservation programs, it is essential to determine which breeding animals will be used, preferentially those with a more significant Iberian genetic component to preserve their origin. This study used a Yucatan black hairless pigs (YBHP) subpopulation to estimate its genetic diversity and population structure. One hundred four adult pigs were selected for the absence of hair, black skin (without spots), black hoof, and straight snout. The porcine-GGP-50K chip was used for SNP genotyping in YBHP, and information on Iberian and Yucatán hairless pigs from the United States (USYU) was taken from databases. All analysis was performed using PLINK v1.9 and v2.1 software. Inbreeding and fixation index values were lower in YBHP, with high observed heterozygosity and allogamy index values, which agree with those obtained in the populations of Canarias and Chato Murciano. According to the clusters generated by the “Genome-Wide Identity by State” analysis, four groups were identified, one of which included pigs from Guadyerbas, USYU, and YBHP. Between populations, YBHP was closely related to the hairless pigs from Guadyerbas, USYU, and Canarias. Principal component analysis showed the same result. According to the results obtained from the runs of homozygosity investigation, aimed to get pools consensus of regions of overlapping, 119 SNPs associated with genes and biological processes were identified. The BMP7 and NSUN2 genes were associated with epithelial cell differentiation, morphogenesis, and epithelial development. For nutrient metabolism: energy, the HADHA, PPARA, ADD1/SREBF1, and FAT1genes were identified.

In degree incest negative influence of inbreeding is established on sheep's productive qualities in comparison with contemporaries with inbreeding in a degree of a close and moderate alliance. The system of a coupling of the wombs is developed, excluding inbreeding depression on productive qualities of animals and allowing to carry out repairs a livestock in a small population due to own reproduction

Research of the peculiar features of correlation parameter of production indices of 870 mongrel inbred sheep with the various inbreeding coefficients was realized in the conditions of the Republic of Belarus. In course of study there was stated the one-sided influence of inbreeding on phenotypic indices of pair, individual and cumulative pair correlation genetic correlations of sheep productivity. The majority of them were the statistically authentic values with P less than 0,1 - 0,001. It was stated that coefficient variability of genetic correlation of wool productivity rendered influence on sheep inbreeding degree among which there were marked off animal units with inbreeding in degree of consanguinity with the coefficients of higher statistical confidence (with P less than 0,01 - 0,001) than animal units with degrees of close or low relationship and outbred animal units - (P less than 0,1 - 0,01). The majority of ewe productive quality correlation factors with a different inbreeding degree proved to be positive and authentic and could be used for an estimation of correlations between traits in selection process for population perfection