Afeeding trial was conducted in layers for a period of8 weeks (23-30 weeks old) to evaluate the effect of chromium picolinate supplementation on egg yolk cholesterol and egg chromium content in layers.Atotal of (n=120) layers were randomly distributed in completely randomized design into 4 treatmentgroupseachwith2 replicates of 5chicks.The layers of treatment group T1(control)were provided water without chromiumwhile those of T2,T3andT4were provided water containing 200, 400 and 600 ppb chromium / litre respectively.At the end of feeding trial, six eggs from each replicate, on last three days were used for egg yolk cholesterol and egg chromium studies. The results indicated that the total cholesterol andLDL cholesterol content of eggs were significantly (P0.05) reduced and HDL-cholesterol content significantly increased in 400 and 600 ppb chromium supplemented group of layers. Whereas chromium content of eggs increased with increasing levels of chromium supplementation. It was concluded that organic chromium supplementation up to 600 ppb level through water may be advisable to reduce egg yolk total cholesterol and LDL- cholesterol and improved HDL-cholesterol and egg chromium content.

In the conditions of the Republic of Belarus there was studied the efficiency of application of national mineral additives (mineral feed additive produced on the basis of dolomitic meal) in rations of milking cows. In course of the study there were analyzed physical and chemical blood indexes; hematological indexes of cows; biochemical blood indexes; mineral composition of blood; natural resistance of cows. As a result of the realized study it was established, that an optimum dose of a dolomitic meal for milking cows during the winter period was 0,3% per dry matter of a diet. There was proved the possibility of increasing of a daily average milk yield of cows on 11,7%, fat and protein content in milk - on 0,04 - 0,06%, as well as lowering of quantity of somatic cells on 13,6%. Application of a national mineral additive rendered the positive influence on blood indices to what that was proved by increasing of erythrocytes (on 10,9%), thrombocytes (on 5,4%), haemoglobin (on 6,5%), crude protein (on 10,6%), and also macro- and trace elements. Introduction of a dolomitic meal into cow diets made it possible to increase the indices of natural resistance of cows on 0,5 - 4,0%.

In the conditions of the Republic of Belarus there was realized a comparative study of peculiar features of influence of combined application of Khelavit preparation and protein-vitamin-mineral feed supplements Khendriks and Spaeta-kontsentrat on health status of cows and quality of obtained cow milk after application of these preparation for the preventive treatment of osteodystrophy. In course of study there were analyzed haematologic and biochemical blood indexes of cows after application of the experimental preparations. Results of physical and chemical indexes of milk were presented. Research results showed that the analyzed protein, vitamin and mineral feed supplements caused the normalization of biochemical blood indexes in comparison with animal of a control group. Besides, application of mentioned above drugs promoted the increasing of veterinary and sanitary quality and technological properties of produced milk.

In the conditions of the Republic of Belarus there was analyzed the influence of inclusion into broiler chickens diets of probiotoc preparation Bifidoflorin zhidkij (liquid) and prediotic veterinary drug Biofon AIL on the natural resistance, hematopoiesis, growth, metabolic function, development and viability of broiler chickens. In course of the study there was analyzed the dynamics of total haemoglobin, total protein of blood serum, albumins and globulins of broiler chickens which were fed with veterinary drugs probiotoc Bifidoflorin zhidkij and prediotic Biofon AIL. Indexes of chicken viability and life weight gain were marked. Research results showed that application of the presented veterinary preparations rendered the growth promoting action, lowering of disease incidence, increasing of chicken viability, increasing of live weight gain and stimulation of metabolic processes in the most intense period of poultry growing. All these factors were expressed in highest degree after the combined application of the probiotic and prebiotic veterinary drugs.

In the conditions of the Republic of Belarus there was analyzed the efficiency of application multi-enzyme preparations (drugs) Ehkozim (contained beta-glucanases; endo-xilanase; cellulose) and Vitazim (contained complex of enzymatic carbohydrases: xylanase; cellulose; beta-glucanases) in diets of lying hens. Vitazim was applied for destruction of complex structures: dietary fibre, protein, starch. Ehkozim was applied for albuminolysis of the main nonstarch polysaccharides of fodders. It was established that application of preparations in feeding of lying hens promoted the increasing of biological value of poultry meat, and prove to be economically expedient. Poultry meat of analyzed samples in accordance with physical, chemical and bacteriological indices, as well as in accordance with biological value and harmlessness was not worse than meat of control samples. As a result of the realized bacteriological research of all experimental samples of meat and internal organs there were not stated microorganisms Е. coli, S. aureus, bacteria of sort Proteus, B. сеreus and sulfate-reducing clostridium, salmonellas.

A technology of application autolysis of fodder yeasts (AFY) for the production of products with higher protein content, digestible aminoacids and other nutritive and biologically active substances in comparison with the standard fodder yeasts (provit) was tested in the conditions of the Republic of Belarus by an example of three groups of swine. Animals of the first (control) group were fed with combined feed SK-26 with addition of 2% of provit. Animals of the second group were fed with combined feed SR-26with addition of 2% of AFY, the third group - with addition 4% of AFY. Provit and AFY were included into combined feed instead of excluded protein components in equivalent number. Research results showed that autolysis of fodder yeasts did not render negative influence on productivity of fattening stores. Average daily weight gain of stores was 637-674 g. Calculation of economic efficiency of combined feeding application of 2 and 4% of AFY showed that application of 2% AFY was more economically profitable

Investigation of influence of probiotic Dialact and immunostimulant Alveozan on digesting of nutritive substances by broiler chickens of Kobb-500 cross, as well as control over their individual development were realized in the conditions of the Republic of Belarus. The first (control) group of chicken was given standard well-balanced ration. Chickens of the second group were administrated immunostimulant Alveozan in dose of 10 mkg/kg of live weight with drinking water once a day in course of 5 days, with 10 days interval till the end of the growing period. Chickens of the third group were administrated preparation Dialact in dose of 0,1-0,2 ml with drinking water once a day in course of 3 days, with 14 days interval till the end of growing period. Chickens of the fourth group were given Alveozan in dose of 10 microgram/kg of live weight once a day in course of 5 days with 10 days interval, and Dialact in dose 0,1-0,2 ml once a day in course of 3 days, with 6 and 14 days interval. Research results showed that complex application of probiotic Dialact and immunostimulant Alveozan increased the viability of chickens on 100%, average live weight - on 5,1%, average daily weight gain - on 5,1%. Administration of Dialact and Alveozan, both separately and in complex, increased the digestibility of nutritive substances of mixed fodders: application of nitrogen increased on 1,93-6,38%, application of calcium decreased on 10,41-12,54%, phosphorus use increased on 2,38%

Research of the influence of biologically active preparations of natural origin on zoological indices and quality of animal products was studied by the example of their application in broiler chicken diets in the conditions of the Republic of Belarus. On the basis of realized research it was established, that application of biologically active substances immunoamplifier Alveozan, probiotic Dialakt, probiotic Bifidoflorin liquid, prebiotic Biofon and prebiotic Biofon AIL (produced in the Republic of Belarus) did not render negative effect on quality of animal products (all studied meat samples had high quality). The received results testify to necessity of complex application of the above-stated preparations. Application of biologically active preparations made it possible to increase livability of growing birds on 100%, average live weight increase from 1,9 up to 5,1%, daily average weight gain - from 1,9 up to 5,1%, improvement of feed conversion ratio - from 18,3 up to 21%. All studied biologically active preparations made it possible to restore the physiological environment in poultry intestines, normal flora, to suppress the growth of pathogenic microorganisms. The above mentioned preparations could be applied both with preventive, and with the medical purposes

There was studied a preventive efficiency of complex additive Felutsen and its influences on the metabolic status of pregnant dry cows and the indicators characterizing animal yield, received from these cows. Felutsen is the carbon-vitamin-mineral additive containing a complex of carbohydrates, vitamins A, D, Е, micro-and macro elements (sodium, chlorine, calcium (Сa), phosphorus, magnesium (Mg), sulfurs, Cu, Zn, Co, Mn, selenium, iodine) in number of 300g/animal. At cows after calving metabolism disorders are caused by disorders of liver functional activity. Application of complex additive Felutsen to pregnant dry cow allows to carry out successfully preventive maintenance of metabolism disorders, including micro-and macro element metabolism. Use of Felutsen is effective preventive maintenance of pre-natal development disorders of calves, developments of oligotrophy in the postnatal period, raises safety and growth intensity of increase. The most considerable distinctions are revealed in group of cows at which the additive was applied in the form of a briquette to which there was an easy approach. In the tabular form the indicators characterizing the basic metabolic processes, an exchange of macro elements and microelements at cows are presented at application of this additive, and also body weight, disease and safety of the calves received from cows control and test groups. | Целью работы стало изучение профилактической эффективности комплексной добавки Фелуцен и её влияния на метаболический статус стельных сухостойных коров и показатели, характеризующие приплод, получаемый от этих коров. Фелуцен – это углеродно-витаминно-минеральная добавка, содержащая комплекс углеводов, витаминов А, Д, Е, микро- и макроэлементов (натрий, хлор, кальций (Сa), фосфор (Р), магний (Mg), серу, Cu, Zn, Co, Mn, селен, йод) в количестве 300 г/животное. У коров после отёла нарушения метаболизма обуславливаются нарушениями функциональной активности печени. Применение комплексной добавки Фелуцен стельным сухостойным коровам позволяет успешно проводить профилактику обменных нарушений, в том числе и обмена макро- и микроэлементов. Использование Фелуцена является эффективной профилактикой нарушений внутриутробного развития телят, развития гипотрофии в постнатальный период, повышает сохранность и интенсивность роста приплода. Наиболее значительные различия выявлены в группе коров, у которых добавка применялась в виде брикета, к которому был свободный доступ. В табличной форме представлены показатели, характеризующие основные метаболические процессы, обмен макро- и микроэлементов у коров при применении этой добавки, а также живую массу, заболеваемость и сохранность телят, полученных от коров контрольной и опытных групп.