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Antibody response to Raboral VR-G® oral rabies vaccine in captive and free-ranging black-backed jackals (Canis mesomelas)
2022
Koeppel,Katja N. | Geertsma,Peter | Kuhn,Brian F. | van Schalkwyk,Ockert L. | Thompson,Peter N.
Rabies is a zoonotic disease that remains endemic in large parts of southern Africa because of its persistence in wildlife and domestic dog vectors. The black-backed jackals (Canis mesomelas) is primarily the wildlife vector responsible for rabies outbreaks in northern parts of South Africa. Two trials were carried out to investigate antibody responses to the oral rabies vaccine Raboral V-RG® in black-backed jackals under captive and free-ranging conditions. In captive jackals 10/12 (83%; 95% confidence interval [CI]: 52% - 98%), seroconverted after single oral vaccination. Nine captive jackals had protective antibody titres (> 0.5 IU/mL) at 4 weeks (median: 2.1 IU/mL; inter quartile range [IQR]: 0.6-5.7) and 10 jackals had at 12 weeks (median: 3.5 IU/mL; IQR: 1.5-8.3) and three maintained antibody titres for up to 48 weeks (median: 3.4 IU/mL; IQR: 2.0-6.3). Four sites were baited with Raboral V-RG® vaccine for wild jackals, using fishmeal polymer and chicken heads. Baits were distributed by hand or from vehicle at three sites in north-eastern South Africa, with an average baiting density of 4.4 baits/km² and at one site in central South Africa, at 0.12 baits/km². This resulted in protective antibody titres in 3/11 jackals (27%; 95% Cl: 6-61) trapped between 3 and 12 months after baiting in north-eastern South Africa, compared with 4/7 jackals (57%; 95% Cl: 18-90) trapped after 3-18 months in central South Africa. This study shows the potential utility of oral rabies vaccination for the control of wildlife-associated rabies in north-eastern and central South Africa, but extensive studies with wider distribution of bait are needed to assess its potential impact on rabies control in wild jackals.
اظهر المزيد [+] اقل [-]Protective levels of canine distemper virus antibody in an urban dog population using plaque reduction neutralization test
2004
Oyedele, O.I. (Witwatersrand Univ., Johannesburg (South Africa). Anatomical Sciences School) | Oluwayelu, D.O. | Cadmus, S.I.B. | Odemuyiwa, S.O. | Adu, F.D.
Isolation of serovar C-3 Haemophilus paragallinarum from Zimbabwe: A further indication of the need for the production of vaccines against infectious coryza containing local isolates of H. paragallinarum
2002
Bragg, R.R. (Free State Univ., Bloemfontein (South Africa). Microbiology and Biochemistry Dept.)
Changes in the incidences of the different serovars of Haemophilus paragallinarum in South Africa: a possible explanation for vaccination failures
1996
Bragg, R.R. | Coetzee, L. (Pretoria Univ., Onderstepoort (South Africa). Dept. of Poultry Diseases) | Verschoor, J.A.
Seroconversion in captive African wild dogs (Lycaon pictus) following administration of a chicken head bait/SAG-2 oral rabies vaccine combination
2003
Knobel, D.L. (Edinburgh Univ., Midlothian (United Kingdom). Tropical Veterinary Medicine Centre) | Liebenberg, A. | Du Toit, J.T.
Vaccination to control an outbreak of Mycoplasma crocodyli infection
2001
Mohan, K. (Zimbabwean Univ., Harare (Zimbabwe). Veterinary Science Faculty) | Foggin, C.M. | Dziva, F. | Muvavarirwa, P.
Field observations on the duration of immunity in cattle after vaccination against Anaplasma and Babesia species
1996
Tjornehoj, K. | Lawrence, J.A. | Whiteland, A.P. (Project GCP/RAF/259/DEN, Lilongwe (Malawi)) | Kafuwa, P.T.
The epidemiology of rabies in Zimbabwe. 1. Rabies in dogs (Canis familiaris)
1999
Bingham, J. | Foggin, C.M. (Central Veterinary Laboratory, Harare (Zimbabwe)) | Wandeler, A.I. | Hill, F.W.G.
Seroprevalence of infectious bursal disease in non-vaccinated indigenous and exotic chickens on selected farms around Gaborone, Botswana
1999
Mushi, E.Z. (Botswana College of Agriculture, Gaborone (Botswana)) | Binta, M.G. | Chabo, R.G. | Ndebele, R.T.
Experimental infection of vaccinated slaughter ostriches with virulent Newcastle disease virus
1997
Verwoerd, D.J. (Agricultural Research Council, Onderstepoort (South Africa). Onderstepoort Veterinary Inst.) | Gerdes, G.H. | Olivier, A. | Williams, R.
