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Study on hematological alterations in experimental lead toxicosis in Long Evans rats
2017
Gani, M. U. | Siddiqui, M. S. I. | Islam, K. | Ahmed, S. | Rashid, M. H. | Moonmoon, S. | Mostofa, M.
The study of alterations of some hematological parameters in a experimentally induced lead toxicosis were carried out on a total of 15 (15 days old) male weaning Long- Evans (ICDDRB strain) rats. The rats were randomly divided in to three equal groups, each consisting of fiverats. Rats of group A were kept as control (without giving any treatment), group B received lead acetate alone @ 6 mg/ml drinking water and group C receivedlead acetate @ 6 mg/ml plus whole milk (Star ship®) 150 mg/ml drinking water. The result showed a most significantly (p< 0.01) decreased TEC, TLC and Hb%observed on day 56 in group B but in group C, these counts decreased significantly (p< 0.05) on days 56 of experiment. From the study, it was concluded that treatment with lead acetate at low doses has harmfuleffects on experimental animals including hematological alterations.
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